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Comprehensive analysis of peripheral blood free amino acids in MASLD: the impact of glycine-serine-threonine metabolism.
Amino Acids
December 2024
Department of Gastroenterology and Hepatology, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba, 272-8516, Japan.
Little is known about how blood free amino acids (FAAs) change in metabolic dysfunction-associated steatotic liver disease (MASLD). This study aims to identify the imbalance of FAAs in MASLD and explore its correction as a potential therapeutic target. We analyzed plasma FAAs data from 23,036 individuals with steatosis information from a biobank in Japan, and 310 patients with MASLD were enrolled.
View Article and Find Full Text PDFAcute pyelonephritis in adults. Should we adopt the pediatric guidelines?
Urologia
December 2024
Department of Urology & Pediatric Urology, Shaare Zedek Medical Center, Faculty of Medical Science, Hebrew University, Jerusalem, Israel.
Purpose: There are no guidelines, what recommend pro or against cystography for identification of VUR for adults who suffer from first episode of pyelonephritis. The aim of this study was to look at incidence of VUR in adults with first episode of pyelonephritis, and to highlight recommendations for possible reflux investigation in these patients.
Methods: We have performed retrospective review of all patients who admitted at our department over the last decade with the working diagnosis of acute pyelonephritis.
Thyroid Eye Disease and Artificial Intelligence: A Comparative Study of ChatGPT-3.5, ChatGPT-4o, and Gemini in Patient Information Delivery.
Ophthalmic Plast Reconstr Surg
December 2024
Ophthalmology Department, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Israel.
Purpose: This study aimed to compare the effectiveness of 3 artificial intelligence language models-GPT-3.5, GPT-4o, and Gemini, in delivering patient-centered information about thyroid eye disease (TED). We evaluated their performance based on the accuracy and comprehensiveness of their responses to common patient inquiries regarding TED.
View Article and Find Full Text PDFThe Preaponeurotic Fat Advancement Pedicle for Correction of Upper Eyelid Volume Asymmetry: A Case Series.
Ophthalmic Plast Reconstr Surg
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Eyesthetica, Los Angeles, California, U.S.A.
Preoperative volume asymmetry in the upper eyelid sulci can pose a challenge in achieving symmetry after upper eyelid blepharoplasty. Reported methods to improve volume asymmetry include the use of soft tissue filler and various surgical techniques. The authors present 6 cases where a central preaponeurotic fat advancement pedicle was utilized during upper eyelid blepharoplasty for improved upper eyelid symmetry (Fig.
View Article and Find Full Text PDFQuantification and source apportionment of atmospheric oxidation capacity in urban atmosphere by considering reactive chlorine species and photochemical loss of VOCs.
Sci Total Environ
December 2024
Department of Atmospheric Science, School of Environmental Studies, China University of Geosciences, Wuhan 430074, China; Research Centre for Complex Air Pollution of Hubei Province, Wuhan 430074, China. Electronic address:
Atmospheric oxidation capacity (AOC) reflects the potential of the atmosphere in converting primary pollutants into secondary aerosols and ozone (O). In this study, the AOC at an urban supersite in Wuhan, a megacity in central China, was quantified by considering the reactions of volatile organic compounds (VOCs) and carbon monoxide (CO) with atmospheric oxidants (OH, NO, O, and Cl). Photochemical loss of total VOCs (13.
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