This is a scoping review of the PubMed, Scopus, BIREME, SciELO, and Web of Science databases, including publications from December 2019 to May 2020 with the objective of identifying and systematizing the literature on the status of persons with disabilities in the initial months of the COVID-19 pandemic. The review aimed to search for original peer-reviewed articles published in indexed journals, in addition to the specialized gray literature. We reviewed 386 texts and included 33 articles and documents in the study. The review's results pointed to three thematic categories that reflect the main discussions on the theme in the literature: vulnerabilities of persons with disabilities during the pandemic; rights of persons with disabilities in this context; and protective measures and access to information on COVID-19 for persons with disabilities. In the context of the public health emergency, historically marginalized communities such as persons with disabilities run the risk of feeling more vulnerable, suffering deprivations, discrimination in screening plans for care, and prejudices and stigmas that influence decision-making in healthcare and exacerbate preexisting inequalities, making this group more susceptible to illness and lack of social protection. Although persons with disabilities have been acknowledged as a risk group for COVID-19, governments have been slow to develop plans to fight COVID-19 for this population. Few studies have attempted to understand the effects of the COVID-19 pandemic on persons with disabilities, especially in the sense of implementing measures in prevention, control, and protection that guarantee equity in care.
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http://dx.doi.org/10.1590/0102-311X00291720 | DOI Listing |
JAMA Netw Open
January 2025
Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
Importance: There have been limited evaluations of the patients treated at academic and community hospitals. Understanding differences between academic and community hospitals has relevance for the design of clinical models of care, remuneration for clinical services, and health professional training programs.
Objective: To evaluate differences in complexity and clinical outcomes between patients admitted to general medical wards at academic and community hospitals.
Insights Imaging
January 2025
Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montreal, QC, Canada.
Objectives: To compare thoracolumbar fascia (TLF) shear strain between individuals with and without nonspecific low back pain (NSLBP), investigate its correlation with symptoms, and assess a standardized massage technique's impact on TLF shear strain.
Methods: Participants were prospectively enrolled between February 2021 and June 2022. Pre- and post-intervention TLF ultrasound and pain/disability questionnaires were conducted.
J Neurol
January 2025
Jacobs Comprehensive MS Treatment and Research Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
Background: Previous investigations on optical coherence tomography (OCT) in multiple sclerosis (MS) focused on generalizable macular and peri-papillary regions without considering the anatomic variations of the retinal layer thickness.
Objective: This study aimed to assess the utility of parafoveal retinal layer thickness measured by OCT, underscoring its relationships with clinical outcomes in MS.
Methods: In this cross-sectional study, 214 people with MS (pwMS) and 57 age- and sex-matched healthy controls (HCs) were enrolled.
J Neurol
January 2025
Division of Child Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Background: The presented study identified the appropriate ocrelizumab dosing regimen for patients with pediatric-onset multiple sclerosis (POMS).
Methods: Patients with POMS aged 10-17 years were enrolled into cohort 1 (body weight [BW] < 40 kg, ocrelizumab 300 mg) and cohort 2 (BW ≥ 40 kg, ocrelizumab 600 mg) during a 24-week dose-exploration period (DEP), followed by an optional ocrelizumab (given every 24 weeks) extension period.
Primary Endpoints: pharmacokinetics, pharmacodynamics (CD19 B-cell count); secondary endpoint: safety; exploratory endpoints: MRI activity, protocol-defined relapses, Expanded Disability Status Scale (EDSS) score change.
Eur J Trauma Emerg Surg
January 2025
Division of Physiotherapy, Department of Health and Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Purpose: Trauma is known as a leading cause of mortality and injury related disability globally. In South Africa (SA) the socioeconomic burden of trauma is magnified as the working age is most affected. The aim of this study was to describe the proportion of major trauma survivors who returned to work (RTW) during a 6-month period post hospital discharge and to identify the factors associated with the RTW outcome.
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