Genetic Networks That Govern Sexual Reproduction in the Pezizomycotina.

Microbiol Mol Biol Rev

Forestry and Agricultural Biotechnology Institute, Department of Biochemistry, Genetics, and Microbiology, University of Pretoriagrid.49697.35, Pretoria, Gauteng, South Africa.

Published: December 2021

AI Article Synopsis

  • Sexual development in filamentous fungi is regulated by intricate genetic pathways, with mating-type genes acting as key transcription factors controlling gene expression throughout the sexual cycle.
  • The process starts when mating pheromones are exchanged between compatible fungal partners, leading to fertilization and the development of specialized structures for spore formation.
  • This review highlights the genetic networks involved in each stage of the sexual cycle, specifically in filamentous ascomycete fungi, detailing how these processes contribute to their growth and reproduction.

Article Abstract

Sexual development in filamentous fungi is a complex process that relies on the precise control of and interaction between a variety of genetic networks and pathways. The mating-type () genes are the master regulators of this process and typically act as transcription factors, which control the expression of genes involved at all stages of the sexual cycle. In many fungi, the sexual cycle typically begins when the mating pheromones of one mating type are recognized by a compatible partner, followed by physical interaction and fertilization. Subsequently, highly specialized sexual structures are formed, within which the sexual spores develop after rounds of meiosis and mitosis. These spores are then released and germinate, forming new individuals that initiate new cycles of growth. This review provides an overview of the known genetic networks and pathways that are involved in each major stage of the sexual cycle in filamentous ascomycete fungi.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485983PMC
http://dx.doi.org/10.1128/MMBR.00020-21DOI Listing

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