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Finding the optimal access for proximal upper limb artery (PULA) interventions: Lessons learned from the PULA multicenter registry. | LitMetric

AI Article Synopsis

  • The PULA Registry was established to find the best puncture sites for procedures involving the subclavian, axillary, and innominate arteries, focusing on their technical complexities.
  • A study analyzed 272 patients with symptomatic stenosis and 108 with total occlusion of upper limb arteries, finding that the stenotic group had a higher success rate and shorter procedure times than the occlusion group.
  • Ultrasound-guided distal radial artery access proved to be the safest method with no complications, while dual access improved treatment efficacy without significantly increasing adverse events.

Article Abstract

Objective: The multicenter proximal upper limb artery (PULA) Registry was created to study the optimal puncture sites for the interventions involving the subclavian, axillary, and innominate arteries.

Background: Little is known about the optimal vascular access for PULA interventions, despite the well-known technical complexity of these procedures.

Methods: We performed the retrospective analysis of consecutive patients treated for symptomatic steno-occlusive disease of the proximal upper limb arteries between January 2015 and December 2019 in three high-volume centers. Acute thrombotic occlusions were excluded from the study.

Results: Two hundred and seventy-two patients were treated for significant stenosis and 108 for total occlusion. The baseline patient's characteristics were similar, except for the higher median age of the stenotic patients: 68.5 years (31.1; 90.0) versus 64 years (38.0; 86.0) p = 0.0015. Successful revascularization rate was higher in the stenotic group 93.75% (255/272) versus 86.11% (93/108) p = 0.0230, while the procedure length 27 min (8; 133) versus 46 min (7; 140) p = 0.0001 and fluoroscopy times 439 s (92; 2993) versus 864 s (86; 4176) p = 0.0001 were higher in the occlusion group. The main adverse event rate was similarly low. Dual access was used more often to treat occlusions (60.19% (65/108) vs. 11.40% (31/272) p = 0.0001) without significantly increasing the complication rate. The safest access was ultrasound-guided distal radial artery puncture, significantly better than conventional radial access with 0% (0/31) versus 13.6% (18/131) p = 0.0253 complication.

Conclusions: The percutaneous revascularization of proximal upper limb arteries is a safe and effective. Dual access can be applied to increase treatment efficacy, without significantly compromising safety.

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Source
http://dx.doi.org/10.1002/ccd.29967DOI Listing

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