Due to the growing competitive challenges, athletes' mutation between clubs has emerged an area of interest within career development. However, studies aimed at analysing this specific process of adaptation to clubs that lead to success or failure in such career mutations are seldom. We developed a comprehensive understanding of the psychological mutation processes to clubs using a narrative level of McAdams' model of personality. The qualitative method approach used in the Big Three narrative framework (McLean et al., 2019) and good life stories standards (McAdams, 1996) were applied to uncover the components of the narratives of twenty professional basketball players during mutation between clubs. The current study sort to test the links between these narrative components and athlete successful club to club mutation (CCM-successful). On average, the results showed that the participants experienced richer narratives as compared to general population (17.08) = -1.48, < .05. Narratives in the CCM-successful were also richer (Mean = 2.83, SD = .16) as compared to narratives of the CCM-unsuccessful (Mean = 1.63, SD, = .36). The overall club mutation success correlated positively with exploratory processing, meaning-making and agency narrative components. These results suggest that when athletes develop active attitudes seeking for solution and sharing their experience with others, they may build the conditions of adaptability that corresponds to a successful outcome for their mutation. The participants exhibited flexible and proactive behaviours which rendered possible the appropriation of the elements in the environment that favour a positive experience of mutation.
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http://dx.doi.org/10.1016/j.heliyon.2021.e08015 | DOI Listing |
Cancer Gene Ther
December 2024
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Angiosarcomas are a group of vascular cancers that form malignant blood vessels. These malignancies are seemingly inflamed primarily due to their pathognomonic nature, which consists of irregular endothelium and tortuous blood channels. PIK3CA mutations are oncogenic and disrupt the PI3K pathway.
View Article and Find Full Text PDFJ Pathol
January 2025
Institut de Recherche en Santé Digestive (IRSD), Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France.
Patients with familial adenomatous polyposis (FAP) harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. There is no validated treatment, and animal models are not sufficient to study FAP. Our aim was to investigate the early events associated with FAP using the intestinal organoid model in a single-center study using biopsies from nonadenomatous and adenomatous colonic mucosa of FAP patients and from healthy controls (HCs).
View Article and Find Full Text PDFGut
November 2024
Department of Pathology, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
Background: Gastric intestinal metaplasia (IM) is a precancerous stage spanning a morphological spectrum that is poorly represented by human cell line models.
Objective: We aim to establish and characterise human IM cell models to better understand IM progression along the cancer spectrum.
Design: A large human gastric IM organoid (IMO) cohort (n=28), their clonal derivatives and normal gastric organoids (n=42) for comparison were established.
Life (Basel)
September 2024
LUX MED Oncology Hospital, św. Wincentego 103, 03-291 Warsaw, Poland.
This review presents current knowledge on the surgical treatment of endometrial cancer in young patients. Endometrial cancer is the most common gynecological cancer in Europe. Higher morbidity is correlated with obesity, hypertension and diabetes, which are growing worldwide.
View Article and Find Full Text PDFVet Res
September 2024
College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV). In contrast to feline enteric coronavirus (FECV), which exclusively infects enterocytes and causes diarrhea, FIPV specifically targets macrophages, resulting in the development of FIP. The transmission and infection mechanisms of this complex, invariably fatal disease remain unclear, with no effective vaccines or approved drugs for its prevention or control.
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