A novel halogen bonding (XB) bis(iodotriazole)-imidazolium motif is incorporated into the axle component of a [2]rotaxane a discrete chloride anion template directed clipping methodology. H NMR anion titration experiments reveal the interlocked host is capable of strong halide and sulfate oxoanion binding in competitive aqueous-organic CDCl/CDOD/DO (45 : 45 : 10 v/v) solvent mixtures. In comparison to a hydrogen bonding rotaxane analogue, which exhibited no pronounced selectivity between Cl, I and SO, the axle iodo-triazole donor motifs of the XB rotaxane modulate the anion recognition preference towards the lighter halides Cl ≈ Br > SO > I.
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