Objectives: Fetal 2D and 3D fractional limb volume (FLV) measurements by ultrasound can detect fetal lean and subcutaneous mass and possibly percent body fat. Our objectives were to 1) compare FLV measurements in fetuses with fetal growth restriction (FGR) versus small for gestational age (SGA) defined by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG)-supported international Delphi consensus and 2) correlate FLV findings with birth metrics. We hypothesize that FLV measurements will be significantly smaller in FGR versus SGA fetuses and will correlate closer with Ponderal index (PIx) in the neonate than abdominal circumference (AC).
Methods: Patients were categorized as FGR or SGA as defined by ISUOG. Total thigh volume (TTV), volumes of lean mass (LMV), and fat mass volume (FMV) were calculated from 3D acquisitions. Measurements were compared between groups and correlated with birthweight (BW) and PIx (BW/crown-heal length).
Results: The FGR group (n = 37) delivered earlier (37/2 versus 38/0; P = .0847), were lighter (2.2 kg versus 2.6 kg; P = .0003) and had lower PIx (0.023 versus 0.025; P = .0013) than SGAs (n = 22). FGRs had reduced TTV (40.6 versus 48.4 cm ; P = .0164), FMV (20.8 versus 25.3 cm ; P = .0413), and LMV (19.8 versus 23.1 cm ; P = .0387). AC had the highest area under the curve (0.69) for FGR. FMV was more strongly associated with PIx than the AC (P = .0032).
Conclusions: The AC and FLV measurements were significantly reduced in FGR fetuses compared to SGAs. While the AC outperformed FLV in predicting FGR, the FLV correlated best with PIx, which holds investigative promise.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jum.15841 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A study on lane-changing risk evolution of vehicle group based on potential field model in the freeway tunnel approach section.
Traffic Inj Prev
December 2024
Shanghai Municipal Engineering Design Institute Group Co., Ltd., Shanghai, China.
Objective: In the freeway tunnel approach section, lane-changing behaviors and transitions in the driving environment exacerbate traffic flow disruptions, increase driving risks, and lead to a higher accident rate. To this end, this study presents a method to explore the risk evolution process of lane-changing in these sections and evaluate its impact on traffic flow operations surrounding lane-changing vehicles.
Methods: First, a driving risk potential field model based on the field theory, which consists of a vehicle kinetic potential field and a tunnel illumination potential field, is proposed to evaluate the driving risk.
Cyclic and pseudo-cyclic electron pathways play antagonistic roles during nitrogen deficiency in Chlamydomonas reinhardtii.
Plant Physiol
December 2024
Aix Marseille University, CEA, CNRS, Institute of Biosciences and Biotechnology of Aix Marseille, BIAM, CEA Cadarache, Saint Paul-Lez-Durance, 13118, France.
Article Synopsis
- * The study focused on the roles of Proton Gradient Regulator-like 1 (PGRL1) and Flavodiiron proteins (FLV) in photosynthesis under nitrogen scarcity using the algae Chlamydomonas reinhardtii.
- * Findings showed that pgrl1 mutants maintained better photosynthetic performance compared to flvB mutants when nitrogen was low, indicating that PGRL1 and FLV have opposing effects on photosynthesis and carbon storage during nitrogen deficiency.
Predictability of combining Technetium-99m-galactosyl human serum albumin single-photon emission computed tomography/computed tomography and indocyanine green clearance test for posthepatectomy liver failure.
Jpn J Radiol
November 2024
Department of Radiology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Purpose: To evaluate the predictive ability of combining Technetium-99m-galactosyl human serum albumin (Tc‑GSA) single-photon emission computed tomography (SPECT)/computed tomography (CT) volume and plasma clearance rate of indocyanine green (ICGK) for posthepatectomy liver failure (PHLF).
Materials And Methods: Fifty patients who underwent Tc-GSA scintigraphy as a preoperative examination for segmentectomy or more from July 2021 to June 2023 were evaluated prospectively. Patients were divided into two groups according to the presence or absence of posthepatectomy liver failure (PHLF).
Ecological spectroscopic methodologies for quantifying co-administered drugs in human plasma by photochemical quantum mechanical simulation.
Heliyon
February 2024
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.
Urinary tract infections (UTIs) constitute the second most prevalent bacterial infections in the elderly demographic. The treatment landscape involves various antibiotics targeting the causative organisms; nevertheless, the emergence of resistance significantly impacts therapeutic effectiveness. Presently, a fixed-dose pharmaceutical combination is advocated to optimize patient outcomes by mitigating the risks of bacterial resistance and associated side effects.
View Article and Find Full Text PDFActivation of sigma-1 receptor ameliorates sepsis-induced myocardial injury by mediating the Nrf2/HO1 signaling pathway to attenuate mitochondrial oxidative stress.
Int Immunopharmacol
January 2024
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China; Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China; Hubei Key Laboratory of Cardiology, Wuhan 430060, China. Electronic address:
Background: Sepsis is a condition that triggers the release of large amounts of reactive oxygen species and inflammatory factors in the body, leading to myocardial injury and cardiovascular dysfunction - an important contributor to the high mortality rate associated with sepsis. Although it has been demonstrated that the sigma-1 receptor (S1R) is essential for preventing oxidative stress, its effectiveness in treating sepsis is yet unknown.
Aim: This study aimed to investigate the role and mechanisms of S1R activation in sepsis-induced myocardial injury.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!