Increasing evidence indicates that a mitochondria-specific stress response referred to as the 'mitochondrial unfolded protein response' (UPR) is activated to maintain mitochondrial integrity and support tumor growth. In this forum article, we discuss the recent advances and current challenges in therapeutically targeting UPR in cancer.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287746 | PMC |
| http://dx.doi.org/10.1016/j.trecan.2021.08.008 | DOI Listing |
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