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Gonadotropin Releasing Hormone Agonists Combined with Hormone Replacement Therapy Significantly Improves Reproductive Outcomes for Patients with Thin Endometrium and Intramural Fibroids in Frozen Embryo Transfer Cycles.
Drug Des Devel Ther
January 2025
People's Hospital of Zhengzhou University, Zhengzhou, Henan, 45003, People's Republic of China.
Background: Both intramural myomas and thin endometrium exert a detrimental influence on the outcomes of assisted reproductive technology (ART). The downregulation of gonadotropin releasing hormone agonists (GnRH-a) is regarded as an effective approach to reducing the size of intramural fibroids and enhancing endometrial receptivity. Consequently, we conducted this study to assess whether the GnRH-a combined with hormone replacement therapy (GnRH-a-HRT) can improve reproductive outcomes in frozen embryo transfer cycles for patients with a thin endometrium (≤7 mm) and intramural fibroids.
View Article and Find Full Text PDFTranscervical resection of myoma (TCRM): Part I.
Taiwan J Obstet Gynecol
January 2025
Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Medicine, Cheng-Hsin General Hospital, Taipei, Taiwan. Electronic address:
Uterine fibroids occur frequently in women during the reproductive age, and they are rarely associated with clinical meaning because of their benign characteristics and asymptomatic clinical presentation. Sometimes, uterine fibroids are symptomatic and associated with compression syndrome, infertility, chronic pelvic pain and heavy menstrual bleeding. All need further intervention and treatment.
View Article and Find Full Text PDFUnintentional exposure to leuprolide acetate during early pregnancy with a huge intramural myoma.
BMJ Case Rep
January 2025
Department of Medicine, University of Hawai'i at Mānoa John A Burns School of Medicine, Honolulu, Hawaii, USA.
Leuprolide acetate is commonly used to reduce the size of myomas before surgery. Initially, it stimulates pituitary gonadotropin secretion, followed by sustained suppression of gonadal function. However, the impact on pregnancy outcomes from inadvertent exposure remains unclear.
View Article and Find Full Text PDFStep-by-step hysteroscopic treatment of International Federation of Gynaecology and Obstetrics type 3 myoma with the cold loop technique.
Fertil Steril
December 2024
Section of Obstetrics and Gynecology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy. Electronic address:
Objective: To demonstrate the "cold loop technique" for the hysteroscopic treatment of International Federation of Gynaecology and Obstetrics (FIGO) type 3 myomas.
Design: Step-by-step demonstration of the technique using educative video.
Subjects: A 45-year-old patient with infertility with repeated oocyte donor in vitro fertilization failures affected by a FIGO type 3 myoma.
PATHOMORPHOLOGICAL AND CLINICAL CHARACTERISTICS OF THE UTERUS IN COMBINED ADENOMYOSIS AND MYOMA.
Georgian Med News
October 2024
Azerbaijan Medical University, Department of Obstetrics and Gynecology II, Baku, Azerbaijan.
The Aim Of The Study: to examine the pathomorphological and clinical characteristics of the uterus in the combined form of fibroids and adenomyosis.
Methods: The research work was conducted within the framework of the scientific program of the Department of Obstetrics and Gynecology II at Azerbaijan Medical University for the years 2021-2024. In the course of this study, a comprehensive clinical, laboratory, and instrumental prospective examination was conducted on 113 patients aged 30 to 50 years (mean age 42,0±1,8 years) with combined adenomyosis and uterine fibroids.
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