This study aimed to estimate the impact of alcohol use on mortality and health among people 69 years of age and younger in 2016. A comparative risk assessment approach was utilized, with population-attributable fractions being estimated by combining alcohol use data from the Global Information System on Alcohol and Health with corresponding relative risk estimates from meta-analyses. The mortality and health data were obtained from the Global Health Observatory. Among people 69 years of age and younger in 2016, 2.0 million deaths and 117.2 million Disability Adjusted Life Years (DALYs) lost were attributable to alcohol consumption, representing 7.1% and 5.5% of all deaths and DALYs lost in that year, respectively. The leading causes of the burden of alcohol-attributable deaths were cirrhosis of the liver (457,000 deaths), road injuries (338,000 deaths), and tuberculosis (190,000 deaths). The numbers of premature deaths per 100,000 people were highest in Eastern Europe (155.8 deaths per 100,000), Central Europe (52.3 deaths per 100,000 people), and Western sub-Saharan Africa (48.7 deaths per 100,000). A large portion of the burden of disease caused by alcohol among people 69 years of age and younger is preventable through the implementation of cost-effective alcohol policies such as increases in taxation.
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http://dx.doi.org/10.3390/nu13093145 | DOI Listing |
Diagnostics (Basel)
November 2024
National Scientific Shared Laboratory of Biotechnology, National Center of Biotechnology Limited Liability Partnership, Astana 010000, Kazakhstan.
Introduction: Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and fatal disease. The aim of this study was to evaluate the association of polymorphism of the type 2 bone morphogenetic protein receptor gene (BMPR2) with the risk of IPAH development in an ethnic group of Kazakhs. We also describe the clinical and hemodynamic characteristics and outcomes of patients with and without carriers of BMPR2 gene mutations in IPAH.
View Article and Find Full Text PDFMed J Islam Repub Iran
August 2024
Department of Geriatrics, School of Social Welfare, University of Welfare and Rehabilitation Sciences, Tehran, Iran.
Open Med (Wars)
December 2024
Department of Orthopedics, Shaoxing People's Hospital, Shaoxing, 312000, Zhejiang, China.
Background: Osteosarcoma, a highly malignant skeletal tumor, primarily affects children and adolescents. Autophagy plays a crucial role in osteosarcoma pathophysiology. This study utilizes bibliometric analysis to evaluate current research on autophagy in osteosarcoma and forecast future directions.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Operational and Implementation Research, ICMR- National Institute for Research in Reproductive and Child Health- HTA Regional Resource Hub, Mumbai, Maharashtra, India.
Proc Natl Acad Sci U S A
December 2024
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115.
The Planetary Health Diet (PHD), also known as the EAT-Lancet reference diet, was developed to optimize global dietary quality while keeping the environmental impacts of food production within sustainable planetary boundaries. We calculated current national and global adherence to the PHD using the Planetary Health Dietary Index (PHDI). In addition, we used data on diet and mortality from three large US cohorts (n = 206,404 men and women, 54,536 deaths) to estimate the total and cause-specific mortality among adults 20 y of age and older that could be prevented by shifting from current diets to the reference PHD.
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