There is a lack of evidence to show prevalence of laryngopharyngeal reflux (LPR) and the association between LPR and dietary factors. Adolescents consume the most amount of free sugars among the Chinese population. We conducted this study to investigate the prevalence of LPR in Chinese adolescents and explore the association between free sugars consumption and LPR. A cross-sectional study was conducted on 1517 middle school students in Hunan, China. An online questionnaire was applied to collect data on the condition of LPR, consumption of free sugars and other self-reported covariates. Height, weight and waist circumference were collected by anthropometric measurements. Logistic regression was applied to assess the association between LPR and free sugars consumption. The mean and standard deviation of free sugars consumption was 53.14 ± 44.75 (g/d). The prevalence of LPR was 8.11%. A positive association was observed between LPR and higher free sugars consumption after adjusted multiple covariates, with adjusted odds ratio (95% confident interval) of 1.656 (1.125-2.438). The prevalence of LPR among Chinese adolescents was high. Further analytic studies with strict design are required to test the association between LPR and free sugar consumption. Systematic strategies and policies should to be developed to reduce the intake of free sugars in order to prevent LPR.
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http://dx.doi.org/10.3390/nu13093012 | DOI Listing |
Chembiochem
December 2024
University of California Los Angeles, Dept. of Chemical And Biomolecular Engineering, 5531 Boelter Hall, 420 Westwood Plaza, 90095, Los Angeles, UNITED STATES OF AMERICA.
While sugar-containing natural products are commonly biosynthesized via glycosyltranferases using sugar-UDP as the electrophile, nature has evolved alternative strategies of glyco-modification to expand the diversity of natural products. Hydroxyl groups on sugars can serve as nucleophiles in the release of polyketide products from polyketide synthases. Herein, we demonstrate a highly reducing polyketide synthase (HRPKS) from the biocontrol fungus Trichoderma afroharzianum T22, which is terminated with a carnitine acyltransferase (cAT) domain, catalyzes the biosynthesis of a d-galactose esterified polyketide named as trichogalactin.
View Article and Find Full Text PDFFront Immunol
December 2024
Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Background: Glucose-to-lymphocyte ratio (GLR) plays an important role in the prognosis of various tumors. The aim of this study was to comprehensively evaluate the prognostic value of GLR in solid tumors through the meta-analysis.
Methods: A comprehensive search of eligible studies was performed by scrutinizing the Pubmed, Embase and Web of science databases until May 30, 2024.
Int J Biol Macromol
December 2024
State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei University, Wuhan 430062, PR China; School of Life Science, Hubei University, Wuhan 430062, PR China. Electronic address:
Biobleaching is an eco-friendly strategy that can reduce costs and pollution in the pulp and paper industry. Herein, an effective biobleaching approach was proposed using a novel multi-enzyme complex. The multi-enzyme complex was constructed based on mini-cellulosome scaffolding protein integrated with laccase (BpLac) and xylanase (BpXyn) from Bacillus pumilus.
View Article and Find Full Text PDFFood Chem
December 2024
Hungarian University of Agriculture and Life Sciences, Institute of Food Science and Technology, Department of Food and Analytical Chemistry. Electronic address:
Fat, sugar, theobromine, and caffeine are important compounds in chocolates that influence the physico-chemical and sensory characteristics of the products. These parameters commonly are determined with conventional, time-consuming, environmentally pollutant methods. In this study, near infrared spectroscopy (NIRS) coupled with partial least square regression (PLSR) was used to predict the quantity of these compounds.
View Article and Find Full Text PDFLipids Health Dis
December 2024
Department of Nephrology A, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Background: Diabesity, a co-occurrence of diabetes and obesity, is a growing public health concern globally. The triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, has been associated with various metabolic disorders. This study aimed to investigate the association between TyG index and new-onset diabesity in a national longitudinal study.
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