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Detection and Phylogenetic Analysis of a Novel Tick-Borne Virus in Yunnan and Guizhou Provinces, Southwestern China. | LitMetric

Detection and Phylogenetic Analysis of a Novel Tick-Borne Virus in Yunnan and Guizhou Provinces, Southwestern China.

Pathogens

Key Laboratory of Health Inspection and Quarantine, School of Public Health, Weifang Medical University, Weifang 261053, China.

Published: September 2021

AI Article Synopsis

  • Dabieshan tick virus (DTV) is a newly discovered tick-borne virus that can infect both animals and humans, primarily found in Shandong and Zhejiang Provinces of China.
  • A study sampled 389 ticks from Yunnan and Guizhou Provinces, finding DTV in 2.43% of ticks in Yunnan and 3.28% in Guizhou, including its first detection in these regions.
  • Phylogenetic analysis revealed that DTV from these provinces shares over 94% genetic similarity with isolates from Hubei and Shandong, indicating that DTV is likely widespread in southwestern China.

Article Abstract

Dabieshan tick virus (DTV) is a novel tick-borne virus with the potential to infect both animals and humans. It has been confirmed that DTV is widely distributed in Shandong and Zhejiang Provinces. In this study, a total of 389 ticks were sampled from Honghe city of Yunnan Province and Bijie city of Guizhou Province, and then divided into 148 pools according to the location and species. QRT-PCR and nested PCR were performed to confirm the presence of DTV. The results showed a minimum infection rate of 2.43% (5/206) in Yunnan Province and 3.28% (6/183) in Guizhou Province, respectively. Interestingly, DTV was identified in for the first time besides . Phylogenetic analysis showed that DTV from Yunnan and Guizhou Provinces shared over 94% identity with isolates derived from Hubei and Shandong Provinces, and DTV was relatively conservative in evolutionary dynamics. These findings provide molecular evidence of Dabieshan tick virus in different species of ticks from unrecognized endemic regions and suggest that DTV may be widely prevalent in southwestern China.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465720PMC
http://dx.doi.org/10.3390/pathogens10091143DOI Listing

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