is one of the main causative agents of human diarrhea. Pigs are a reservoir and the most common source of infection for humans. The aim of this study was to analyze the expression of and genes in strains with different enterotoxic properties, isolated from humans and pigs. The experiment involved two groups of strains producing and not producing enterotoxin YstA, which were isolated from humans and pigs. All strains were and -positive. The expression of and genes was analyzed by quantitative real-time PCR (qPCR). The relative expression level of the gene was significantly higher than the expression level of the gene in strains isolated from humans with clinical symptoms of yersiniosis. In other strains, a significant decrease in gene transcription was observed, and the relative expression level of the gene was significantly higher than the expression level of the gene. Statistically significant differences were not observed in either group of strains isolated from pigs. The results of our study revealed a correlation between mRNA expression levels of and genes in strains isolated from humans.
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| http://dx.doi.org/10.3390/pathogens10091136 | DOI Listing |
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