AI Article Synopsis
- SM is a Gram-negative bacterium linked to increased infections since 1913, primarily affecting immunocompromised patients and newborns in ICUs and NICUs.
- The study investigated the genetic connections between clinical strains of SM found in hospitals and environmental strains using PFGE technology.
- Findings revealed distinct groups of related SM strains across different hospital wards, allowing for quick identification and intervention strategies to control the spread of the bacterium.
Article Abstract
(SM) is a Gram-negative bacterium that is frequently found in the environment. Since 1913, when its pathogenicity was first demonstrated, the number of infections caused by SM has increased. There is ample evidence that SM causes nosocomial infections in immunocompromised or critically ill patients admitted to the intensive care units (ICUs), but also in newborns admitted to neonatal ICUs (NICUs). In this study, we evaluated the possible genetic correlation by PFGE between clinical and environmental SM strains from NICU and ICU and compared the genetic profile of clinical strains with strains isolated from patients admitted to other wards of the same hospital. We found distinct clonally related groups of SM strains circulating among different wards of a large university hospital. In particular, the clonal relationship between clinical and environmental strains in NICU and ICU 1 was highlighted. The identification of clonal relationships between clinical and environmental strains in the wards allowed identification of the epidemic and rapid implementation of adequate measures to stop the spread of SM.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8472797 | PMC |
| http://dx.doi.org/10.3390/ijerph18189814 | DOI Listing |
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