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Infection and Extragastric Diseases-A Focus on the Central Nervous System. | LitMetric

AI Article Synopsis

  • There is growing evidence that infections, typically known for causing gastrointestinal issues, may also contribute to a variety of extragastric diseases affecting different systems in the body, including neurological disorders.
  • This review specifically examines the connection between infection and neurological disorders, emphasizing the impact on the gut-brain axis and changes in gut microbiota due to infections.
  • Most current research on the link between infection and neurological impairments primarily concentrates on a specific type of infection, though this area is still developing.

Article Abstract

() is most known to cause a wide spectrum of gastrointestinal impairments; however, an increasing number of studies indicates that infection might be involved in numerous extragastric diseases such as neurological, dermatological, hematologic, ocular, cardiovascular, metabolic, hepatobiliary, or even allergic diseases. In this review, we focused on the nervous system and aimed to summarize the findings regarding infection and its involvement in the induction/progression of neurological disorders. Neurological impairments induced by infection are primarily due to impairments in the gut-brain axis (GBA) and to an altered gut microbiota facilitated by colonization. Currently, regarding a potential relationship between infection and neurological disorders, most of the studies are mainly focused on .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8469861PMC
http://dx.doi.org/10.3390/cells10092191DOI Listing

Publication Analysis

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