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http://dx.doi.org/10.18502/ijph.v50i7.6656 | DOI Listing |
Background: CADASIL, linked to NOTCH3 variants, is a primary monogenic cause of vascular dementia, leading to vascular cognitive impairment and dementia (VCID) observable in early stages. The NIH-funded USA CADASIL Consortium aims to explore CADASIL's onset and progression in the USA, crucial due to varying phenotype-genotype associations globally. The consortium will identify biological and clinical markers across the disease spectrum, contributing to clinical trial preparations.
View Article and Find Full Text PDFCureus
December 2024
Psychiatry, Yale School of Medicine, New Haven, USA.
Introduction Following the COVID-19 pandemic, there was adoption of virtual psychotherapy. There are a number of benefits and drawbacks to telehealth video conferencing that are experienced by both clients and clinicians. The current qualitative study sought to outline the advantages and disadvantages that clients and clinicians have personally experienced in virtual versus in-person therapy in an effort to identify the reasons for which one medium may be preferred over another.
View Article and Find Full Text PDFJ Infect Public Health
January 2025
Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Via Costantinopoli 16, Naples 80138, Italy; Department of Experimental Medicine - Section of Pharmacology "L. Donatelli", University of Campania "Luigi Vanvitelli", Via Costantinopoli 16, Naples 80138, Italy; Department of Life Science, Health, and Health Professions, Link Campus University, Rome, Italy. Electronic address:
In 2018, Europe experienced a surge in measles cases, revealing the consequences of suboptimal immunization coverage. This trend was exacerbated by long-standing vaccine hesitancy. Parental attitudes toward childhood vaccines have increasingly shifted, influenced by ethical, religious, and safety concerns.
View Article and Find Full Text PDFCurr Cardiol Rep
January 2025
Robert M. Berne Cardiovascular Research Center, and Department of Medicine, DivisionofCardiovascularMedicine,HeartandVascularCenter, University of Virginia, Charlottesville, VA, USA.
Purposeof The Review: In this review article, we aim to provide an overview of the pathophysiology, the clinical features, the therapeutic management and prognosis of patients affected by Multisystemic inflammatory syndrome (MIS) with cardiac involvement, focusing on myocarditis and pericarditis.
Recent Findings: MIS is a multiorgan hyperinflammatory condition due to a cytokine storm following (within 4-12 weeks) SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection. First described in children, it also affects young adults without comorbidities, predominantly males with highly heterogeneous clinical manifestations, including cardiac involvement.
Microorganisms
December 2024
Targeted Therapy Team, Institute for Cancer Research, 237 Fulham Road, London SW3 6JB, UK.
The COVID-19 and mpox crisis has reminded the world of the potentially catastrophic consequences of biological agents. Aside from the natural risk, biological agents can also be weaponized or used for bioterrorism. Dissemination in a population or among livestock could be used to destabilize a nation by creating a climate of terror, by negatively impacting the economy and undermining institutions.
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