Modernization of hospital facilities is one of the objectives of administrators and decision-makers of healthcare systems. Hospital facilities are both complex and critical infrastructures, because they are characterized by high level of interconnections, dynamism, technological innovation, and because they offer health and social essential services. Decision-makers have to implement modernization strategies of hospital facilities in order to guarantee a high standard of care and a resilient response during disasters and emergencies. The critical role played by hospital facilities is acknowledge by the international action programs, including the 2030 Agenda of United Nations for Sustainable Development, and it has been emphasized by the COVID-19 pandemic. The paper illustrates the RADAR-Hospital Facilities methodology (RADAR-HF) developed for the situational assessment of the physical environment of hospital facilities. RADAR-HF provides the decision-makers with an overview of the main aspects for modernization (safety, functionality, sustainability, adaptability, comfort) and substantial information for planning interventions, considering hospital facilities as interconnected systems. The outcomes are represented by ad-hoc designed graphical indicators and overview-tools, that summarize the status-conditions of one or a set of existing hospital facilities, the upgrading needs, and the best occupancy of facilities. Decision-makers could use RADAR-HF to define integrated modernization strategies with resilience improvement, monitor the situation of the facilities, and understand the effectiveness of interventions. The paper ends showing the results obtained in a research project, in which RADAR-HF has been applied to assess the existing hospital facilities of the Friuli Venezia Giulia region (North-East of Italy).
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http://dx.doi.org/10.1016/j.ijdrr.2021.102594 | DOI Listing |
Cancer Imaging
January 2025
Melbourne Theranostic Innovation Centre, Level 8, 14-20 Blackwood St, North Melbourne, VIC, 3051, Australia.
True total-body and extended axial field-of-view (AFOV) PET/CT with 1m or more of body coverage are now commercially available and dramatically increase system sensitivity over conventional AFOV PET/CT. The Siemens Biograph Vision Quadra (Quadra), with an AFOV of 106cm, potentially allows use of significantly lower administered radiopharmaceuticals as well as reduced scan times. The aim of this study was to optimise acquisition protocols for routine clinical imaging with FDG on the Quadra the prioritisation of reduced activity given physical infrastructure constraints in our facility.
View Article and Find Full Text PDFBMC Palliat Care
January 2025
Palliative Care Unit, National Cancer Institute, Rio de Janeiro, Brazil.
Objective: To compare the sociodemographic and clinical profiles of patients with advanced cancer admitted to a tertiary palliative care unit before and during the COVID-19 pandemic.
Methods: This is an analysis of data from patients receiving care before (10/21/2019 to 03/16/2020) and during (09/23/2020 to 08/26/2021) the COVID-19 pandemic. Sociodemographic and clinical data were evaluated.
Commun Biol
January 2025
Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University, Shijiazhuang, 050017, China.
Aberrant autophagy in vascular smooth muscle cells (VSMCs) is associated with the progression of vascular remodeling diseases caused by neointimal hyperplasia. Platelet-derived growth factor-BB (PDGF-BB)-induced vascular remodeling is accompanied by autophagy activation, however, the involvement of circular RNAs (circRNAs) remains unclear. Here, we show the role of PDGF-BB-regulated hsa_circ_0001304 (circ-1304) in neointimal hyperplasia and its potential involvement in VSMC autophagy, while also elucidating the potential mechanisms.
View Article and Find Full Text PDFBMJ Open
January 2025
Lancashire and South Cumbria MND Care and Research Centre, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Background: Caregivers of people with motor neuron disease (MND) face more negative consequences of caregiving than other terminal illnesses. The impact of this caregiver burden can negatively influence bereavement outcomes.
Objectives: This study aims to explore the support needs of caregivers of people with MND, the types of bereavement services they use, or the reasons for not using bereavement services, and understanding the opportunities and barriers to accessing bereavement services.
Clin Exp Optom
January 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Clinical Relevance: Accommodation is crucial for clear near vision and is predominantly affected by presbyopia. The ability to modulate accommodative function with eye drops could offer a pharmacological approach to manage presbyopia.
Background: To investigate the effects of different concentrations of pilocarpine eye drops on ocular accommodation in young volunteers.
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