Second-generation sequencing assistance in the diagnosis of empyema: A case report.

Zhong Nan Da Xue Xue Bao Yi Xue Ban

First Division, Department of Respiratory and Critical Care Medicine, Zhuzhou Hospital, Affiliated to Xiangya School of Medicine, Central South University/Zhuzhou Central Hospital, Zhuzhou Hunan 412007, China.

Published: August 2021

empyema is rare and easy to be misdiagnosed. An 81-year-old male patient showed symptoms with cough, sputum, and fever for 3 days. Community-acquired pneumonia was diagnosed firstly. After anti-infection treatment, the patient was still in fever. Chest radiography showed pleural effusion, closed thoracic drainage was performed and the reddish-brown fluid was drained out. The second-generation sequencing was performed on pleural fluid and was detected. has strict requirements for growth conditions and it difficult to cultivate. The application of second-generation sequencing is helpful to diagnose the pathogen rapidly.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10929971PMC
http://dx.doi.org/10.11817/j.issn.1672-7347.2021.200589DOI Listing

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