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Macropolycytes as a sepsis biomarker.
Morphologie
November 2024
Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal; Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal. Electronic address:
A 16-year-old male patient who underwent a kidney transplant developed a septic shock. A full blood count (FBC) was performed and the presence of monocytosis in the automatic FBC, the overlap between neutrophils and monocytes in the WBC scatter plot, and a "MO blast" flag triggered by the analyzer, led to a peripheral blood film (PBF). PBF revealed the presence of macropolycytes that were erroneously count as monocytes by the analyzer.
View Article and Find Full Text PDFNot only but also: macropolycytes in sepsis by Serratia marcescens.
Hematol Transfus Cell Ther
September 2021
Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal; Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte EPE, Lisbon, Portugal.
Macropolycyte in Pediatrics.
J Pediatr Hematol Oncol
March 2019
Children's Haematology and Cancer Centre, Mount Elizabeth Hospital, Singapore, Singapore.
Macropolycytes are tetraploid neutrophils produced during accelerated myelopoiesis. They have been reported in adults with pernicious anemia, sepsis, and after cytotoxic chemotherapy. Two pediatric cases are reported, one after granulocyte colony-stimulating factor treatment and the other following Kawasaki disease, respectively.
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