Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews.

Diabetes Metab Syndr

Facultad de Medicina Veterinaria y Agronomía, Universidad de las Américas, Santiago, Chile; Departamento de Ciencias Químicas y Biológicas, Universidad Bernardo O'Higgins, Santiago, Chile.

Published: March 2022

AI Article Synopsis

  • The study investigates the inconsistent effects of aloe vera on metabolic health, focusing on its influence on glucose levels and other biomarkers.
  • Four systematic reviews were examined, revealing significant reductions in fasting blood glucose (FBG) and HbA1c in individuals with Type 2 Diabetes Mellitus (T2DM) and pre-diabetes.
  • The findings suggest moderate to high-quality evidence supporting aloe vera's beneficial effects for these conditions.

Article Abstract

Background And Aims: The effects of aloe vera are inconsistent and unclear. The aim of this study is to analyze the effects of aloe vera in metabolic profiles.

Methods: An electronic search of systematic reviews (SRs) was performed in seven databases up to June 2021.

Results: Four SRs met the eligibility criteria. In T2DM, SMD for FBG = -5.61 (p < 0.001). For HbA1c, MD = -0.95 (p = 0.02). In pre-diabetes, SMD for FBG = -1.41 (p = 0.02). For HbA1c, MD = -0.31 (p = 0.02). For TG, MD = -4.99 (p = 0.000).

Conclusion: There exist a moderate to high quality of evidence in favor of the effects of aloe vera in patients with T2DM and pre-diabetes.

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Source
http://dx.doi.org/10.1016/j.dsx.2021.102292DOI Listing

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