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| http://dx.doi.org/10.1016/j.actatropica.2021.106142 | DOI Listing |
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Application of a POCCCA rapid diagnostic test and serology for detection of schistosomiasis in HIV-positive individuals in urban Malawi.
Acta Trop
December 2021
Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany; School of Medicine and Clinical Sciences, Levy Mwanawasa Medical University, Lusaka, Zambia. Electronic address:
Suitability of commercially available POC-CCA tests for schistosomiasis: Considerations for efficiency, reproducibility and decision making criteria for field application in areas of low endemicity.
J Immunol Methods
September 2019
Schistosomiasis Laboratory, Rene Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ), Belo Horizonte, Minas Gerais, Brazil.
Background: Point of care tests would be valuable for field diagnosis. However, high sensitivity will likely be required in low endemicity sets where individuals with low schistosome burden are hard to diagnose.
Methods: Commercially available POC tests (POC-CCA® and Urine CCA (Schisto) ECO Teste®) were evaluated to evidence their potential in low endemicity areas.
Concordance of the point-of-care circulating cathodic antigen test for the diagnosis of intestinal schistosomiasis in a low endemicity area.
Infect Dis Poverty
May 2019
Programa de Pós-Graduação Strictu Sensu em Biologia Parasitária na Amazônia da Universidade do Estado do Pará, Tv. Perebebuí, 2623 - Marco, Belém, PA, 66087, Brazil.
Background: The Kato-Katz technique is recommended worldwide for the diagnosis of intestinal schistosomiasis, detecting parasite eggs in feces of infected people. However, new tests have been developed in order to facilitate diagnosis, e.g.
View Article and Find Full Text PDFInnovative methodology for point-of-care circulating cathodic antigen with rapid urine concentration for use in the field for detecting low Schistosoma mansoni infection and for control of cure with high accuracy.
Trans R Soc Trop Med Hyg
January 2018
Schistosomiasis Laboratory, Rene Rachou Research Center, Oswaldo Cruz Foundation (Fiocruz), Belo Horizonte, Minas Gerais, 30190-002, Brazil.
Article Synopsis
- Accurate and rapid diagnosis is crucial for controlling schistosomiasis, as existing methods like POC-CCA perform poorly in low-endemicity areas.* -
- A new method called POC-CCA filter (FLT) was developed, incorporating a quick urine concentration step that significantly improved diagnostic accuracy in Brazilian endemic areas.* -
- Results showed that POC-CCA FLT had a much higher accuracy rate (up to 100%) compared to the traditional POC-CCA, enhancing its effectiveness in diagnosing cases both before and after treatment.*
Application in Europe of a urine-based rapid diagnostic test for confirmation of Schistosoma mansoni infection in migrants from endemic areas.
Euro Surveill
June 2015
Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany.
In February 2015, a male patient from Eritrea with persistent abdominal pain and rectal bleeding was diagnosed with Schistosoma mansoni infection upon examination of a rectal biopsy. In May 2015, repeated stool microscopy identified S. mansoni infection in another Eritrean patient with abdominal pain and considerable eosinophilia (34%).
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