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| http://dx.doi.org/10.1007/s10067-021-05935-w | DOI Listing |
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Why Current Detection of Vascular Calcification Falls Short and How to Improve on It.
TH Open
October 2024
Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Vascular calcification is a common phenomenon in various vascular diseases, where its presence heralds increased occurrence of adverse disease events, which invariably lead to increased morbidity and mortality in patients. Although the impact of calcification has become apparent, adequate and early detection of the most damaging form of early microcalcification is still in its infancy, preventing reliable identification of locations that would benefit from intervention. In this review, we will provide an overview of the current state-of-the-art noninvasive calcification imaging and its persisting limitations.
View Article and Find Full Text PDFEXPRESS: Screening for Presence of Primary Sjogren's Syndrome in Patients with Autoimmune Thyroid Diseases.
J Investig Med
December 2024
Tanta University Faculty of Medicine, Internal medicine, Tanta, Egypt.
Autoimmune thyroid disorders (AITD) are the most common autoimmune human disorders as thyroid gland is a main target for autoimmunity. The association between rheumatologic and thyroid disorders has long been known, the most common being the association with rheumatoid arthritis. Our study was conducted to screen for the presence of symptoms, signs and immune markers suggesting presence of Sjogren's syndrome among patients with autoimmune thyroid disorders.
View Article and Find Full Text PDFArthralgia and Extraintestinal Manifestations in Crohn's Disease Elevate the Risk of IBD-Related Arthritis over Sacroiliitis.
Rheumatol Ther
December 2024
Institute of Radiology, Department of Medicine, University of Udine, Azienda Sanitaria-Universitaria Friuli Centrale (ASUFC), p.le S. Maria della Misericordia, 15, 33100, Udine, Italy.
Introduction: Inflammatory bowel disease (IBD) related arthritis is the most prevalent extraintestinal manifestation (EIM) of IBD, ranging between 10 and 39%. Magnetic resonance enterography (MRE) is used to assess small bowel disease involvement in Crohn's disease (CD) and can detect signs of sacroiliitis in up to 23.5% of patients.
View Article and Find Full Text PDFIdentification of preoperative predictive markers of periprosthetic joint infection in presumed aseptic revisions of total hip arthroplasty: a retrospective observational study.
Arch Orthop Trauma Surg
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IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano - Milan, 20089, Italy.
Introduction: Periprosthetic joint infections (PJIs) occur at a rate of 1-2% in primary arthroplasties and 4% in revisions, posing a significant healthcare challenge. PJI diagnosis is hindered by absence of a universally accepted diagnostic standard. The primary outcome was to develop a predictive model to identify patients at risk of developing unforeseen PJI subsequent to presumed aseptic revision of total hip arthroplasty (THA).
View Article and Find Full Text PDFFrom Multimorbidity to Network Medicine in Patients with Rheumatic Diseases.
Rheumatol Ther
November 2024
Department of Clinical and Biological Sciences, Centre for Biostatistics, Epidemiology, and Public Health, University of Turin, Turin, Italy.
Article Synopsis
- The shift from a comorbidity-focused approach to a multimorbidity perspective in managing rheumatic diseases emphasizes the presence of multiple diseases, resulting in greater individual and societal impacts, but often leads to fragmented care.
- Network medicine presents a more integrated approach by examining the interactions and connections between different diseases at a biological level, focusing on shared pathways and mechanisms.
- This paradigm shift allows for a holistic understanding of rheumatic diseases, highlighting their interconnectedness through systemic inflammation and immune system dysregulation.
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