AI Article Synopsis
- - The study evaluates the feasibility and safety of prostatic artery embolization (PAE) combined with coil embolization in 95 patients, revealing promising short-term outcomes after treatment for prostate-related issues.
- - Significant improvements were noted in patient symptoms and quality of life; specifically, the International Prostate Symptoms Score improved by an average of -11.2 and quality of life scores by -2.4 after about 10 weeks of follow-up.
- - The procedure showed no adverse events linked to the coil embolization, suggesting it's a safe method that needs more extensive research in future studies.
Article Abstract
Purpose: To describe the feasibility, safety and short-term results of prostatic artery embolization (PAE) performed with adjunctive coil embolization of the main prostatic arteries (PA) following particle embolization.
Materials And Methods: A total of 95 patients who underwent PAE with adjunctive bilateral coil embolization of the PAs following particle embolization between September 2018 and May 2021 were included. The patients had a mean prostate size of 115 ± 64 ml, 18/95 with hematuria symptoms, and 16/95 with indwelling urinary catheters. Coil embolization was performed in the main PAs prior to the bifurcation into the anteromedial and posterolateral branches using detachable microcoils. International Prostate Symptoms Score (IPSS), quality of life (QOL), maximum flow rate (Qmax) and adverse events were recorded.
Results: IPSS were improved by - 11.2 ± 7.9 (n = 49, P < 0.001) and QOL by - 2.4 ± 1.8 (n = 49, P < 0.001) over a mean follow-up of 10.7 ± 7.9 weeks. Qmax did not demonstrate statistical significance. Twelve patients with hematuria (67%) showed improvement or resolution and twelve patients with indwelling or intermittent catheters (75%) were no longer catheter dependent. Two patients underwent a repeat PAE. There were no adverse events which were attributable to coil embolization.
Conclusion: Adjunctive coil embolization of the main PAs following particle embolization is a technically feasible technique with similar short-term clinical outcomes compared to prior studies. This novel technique warrants further prospective investigation with controls.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475843 | PMC |
| http://dx.doi.org/10.1007/s00270-021-02964-5 | DOI Listing |
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