A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8 T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the multiplicative cooperativity between neutralizing antibodies and CD8 T cells and propose how this might be exploited for improving vaccine-induced protective immunity.
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| http://dx.doi.org/10.1016/j.it.2021.08.003 | DOI Listing |
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