AI Article Synopsis
- The study investigates whether patient demographics affect the activation of stroke codes, which help in the timely management of strokes.
- Researchers analyzed data from 265 patients with intracerebral hemorrhage, finding that fewer women and non-white patients had stroke codes activated compared to men and white patients.
- The findings highlight significant gender disparities in emergency stroke care and suggest a need for increased awareness of atypical stroke symptoms to address potential systemic biases.
Article Abstract
Objectives: Routine implementation of protocol-driven stroke "codes" results in timelier and more effective acute stroke management. However, it is unclear if patient demographics contribute to disparities in stroke code activation. We aimed to explore these demographic factors in a retrospective cohort study of patients with intracerebral hemorrhage (ICH).
Materials And Methods: We identified consecutive patients with non-traumatic ICH who presented directly to our Comprehensive Stroke Center over 2 years and collected data on demographics, clinical features, and stroke code activation. We used multivariable logistic regression to examine differences in stroke code activation based on patient demographics while adjusting for initial clinical features (NIH Stroke Scale, FAST [facial drooping, arm weakness, speech difficulties] vs. non-FAST symptoms, time from last-known-well [LKW], and systolic blood pressure [SBP]).
Results: Among 265 patients, 68% (n=179) had a stroke code activation. Stroke codes occurred less frequently in women (62%) than men (72%) and in non-white (57%) vs. white patients (70%). Non-stroke code patients were less likely to have FAST symptoms (37% vs. 87%) and had lower initial SBP (mean±SD 159.3±34.2 vs. 176.0±31.9 mmHg) than stroke code patients. In our primary multivariable models, neither age nor race were associated with stroke code activation. However, women were significantly less likely to have stroke codes than men (OR 0.49 [95% CI 0.24-0.98]), as were non-FAST symptoms (OR 0.11 [95% CI 0.05-0.22]).
Conclusions: Our data suggest gender disparities in emergency stroke care that should prompt further investigations into potential systemic biases. Increased awareness of atypical stroke symptoms is also warranted.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2021.106119 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Artificial Intelligence in Transcranial Doppler Ultrasonography.
Curr Med Imaging
January 2025
UOC Neurologia e Rete Stroke Metropolitana, Istituto delle Scienze Neurologiche di Bologna, Italy.
Transcranial Doppler is an instrumental ultrasound method capable of providing data on various brain pathologies, in particular, the study of cerebral hemodynamics in stroke, quickly, economically, and with repeatability of the data themselves. However, literature reviews from clinical studies and clinical trials reported that it is an operator-dependent method, and the data can be influenced by external factors, such as noise, which may require greater standardization of the parameters. Artificial intelligence can be utilized on transcranial Doppler to increase the accuracy and precision of the data collected while decreasing operator dependencies.
View Article and Find Full Text PDFRadiologist, trainee, and logistical factors impacting the timeliness of CTA head and neck reporting in stroke code activations.
AJNR Am J Neuroradiol
January 2025
From the Tu Lab for Diagnostic Research, Yale School of Medicine, New Haven, CT, USA (OAZ, AEK, SR) and Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA (IDOS, JJ, LHT).
Background And Purpose: Timely reporting of CTA exams impacts management of acute vascular pathology such as large vessel occlusions, arterial dissection, and ruptured aneurysm as well as a variety of acute non-vascular pathologies. In this study, we examine potential modifiable factors impacting the timeliness of CTA reporting performed in stroke code activations.
Materials And Methods: Observational study of stroke code CTA head and neck exams performed at a single health system (3 emergency departments, 1550 inpatient beds) over four years (1/1/2019-12/31/2023).
Nimodipine ameliorates subarachnoid hemorrhage-induced neuroinflammation and injury by protecting mitochondrial function and regulating autophagy.
Hum Cell
January 2025
The First Branch, Hongqi Hospital Affiliated to Mudanjiang Medical University, No. 5 Tongxiang Street, Aimin District, Mudanjiang, 157000, China.
Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke, and the neuroprotective effects of nimodipine following SAH have been well-documented. Sirtuin 3 (SIRT3), a mitochondrial nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, plays a significant role in mitigating oxidative stress in various neurodegenerative conditions. However, the role of SIRT3 in the neuroprotective mechanisms of nimodipine after SAH remains unclear.
View Article and Find Full Text PDFPediatric Attention-Deficit/Hypearativity Disorder and Disruptive Mood Dysregulation Disorder: Analyzing National Treatment Trends.
J Pediatr
January 2025
Department of Psychiatry and Behavioral Health, Pennsylvania State College of Medicine, Hershey, PA.
Objective: This study investigated how a disruptive mood dysregulation disorder (DMDD) diagnosis infleunces treatment selection and sequencing in children with attention-deficit/hyperactivity disorder (ADHD).
Study Design: This multicenter, population-based, retrospective cohort study analyzed data from TriNetX Research Network (June 2013 through July 2024). Youth with ADHD (without DMDD) formed the control cohort (n=631,295).
Redox imbalance driven epigenetic reprogramming and cardiovascular dysfunctions: phytocompounds for prospective epidrugs.
Phytomedicine
January 2025
Post-graduate Department of Biotechnology, Utkal University, Bhubaneswar, 751004, Odisha, India.; Centre of Excellence in Integrated Omics and Computational Biology, Utkal University, Bhubaneswar 751004, Odisha, India.. Electronic address:
Background: Cardiovascular diseases (CVDs) are the major contributor to global mortality and are gaining incremental attention following the COVID-19 outbreak. Epigenetic events such as DNA methylation, histone modifications, and non-coding RNAs have a significant impact on the incidence and onset of CVDs. Altered redox status is one of the major causative factors that regulate epigenetic pathways linked to CVDs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!