Background: For older adults, osteoarthritis (OA) is a common chronic disease that may cause pain, stiffness, and even disability of the affected knee joints. Aromatherapy might presumed to be an alternative and supplemental therapy.
Primary Study Objective: To investigate the effects of aromatherapy on relieving knee pain and improving physical functions among older adults with OA.
Methods/design: A true experimental design with randomized assignment of both treatment (aromatherapy) and control (placebo) groups was used for this study.
Participants: Volunteers from 3 local communities aged ≥50 y with self-reported OA-related knee pain were recruited.
Interventions: A synergistic blend of essential oils diluted to a concentration of 3% was administered to participants in treatment (essential oil) group, whereas mineral oil without essential oil was applied to participants in control (placebo) group. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), including subscales of pain, stiffness, and physical function, was employed to record scores before intervention, 4 wk postintervention, and 8 wk postintervention. Pain scores were also measured and collected by using the visual analog scale at the above counterparts. The Stata v.13 software was used to perform referent statistics with a significance level (α) of 0.05 adopted.
Results: The progressive linear model showed that continuous use of essential oils for 8 wk not only relieves pain immediately, but also further reduces the pain scores of participants, thus proving the long-term effect of aromatherapy on alleviating knee arthritis. Repeated measures analysis of variance further showed that time (intervention duration) is an important factor affecting all outcome scores. Except for stiffness subscales measured by WOMAC, all interactions between groups were significant.
Conclusions: Aromatherapy is validated to be an effective alternative therapy in improving clinical outcomes for patients with OA-induced knee conditions. In addition, longer intervention duration (8 wk instead of 4 wk) yielded better treatment results for participants.
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PLoS One
January 2025
Division of Biotechnology, Department of Agronomy and Plant Breeding, College of Agricultural and Natural Resources, University of Tehran, Karaj, Iran.
Objective: The aromatic profile of Rosa canina L. petals hold immense potential for the fragrance and pharmaceutical industries. This study aims to investigate the chemical composition and gene expression patterns across different floral development stages to uncover the biosynthetic pathways of floral scent.
View Article and Find Full Text PDFChem Biodivers
January 2025
Department of Chemistry, Faculty of Science, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Lantana montevidensis (Spreng.) Briq. is a shrub native to South American countries.
View Article and Find Full Text PDFChem Biodivers
January 2025
Vietnam National University Hanoi, VNU University of Science, 19 Le Thanh Tong, Hoankiem, VIET NAM.
The current study first describes the chemical profiles of essential oils from Vietnamese Chromolaena odorata fresh stem barks and leaves. The gas chromatography-flame inonization detection/mass spectrometry (GC-FID/MS) analysis revealed that α-pinene (6.97-38.
View Article and Find Full Text PDFChem Biodivers
January 2025
CSIR-CIMAP: Central Institute of Medicinal and Aromatic Plants CSIR, Botany and Pharmacognosy, Kukrail Picnic Spot Road, 226015, Lucknow, INDIA.
Cannabis sativa L. is an important medicinal plant with high commercial value. In recent years, the research interest in cannabidiol (CBD) and terpene-rich cannabis has been rapidly expanding due to their high therapeutic potential.
View Article and Find Full Text PDFActa Parasitol
January 2025
Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Ad Dawadimi, Shaqra, 17464, Saudi Arabia.
Purpose: The present experimental study seeks to evaluate the in vitro and in vivo effects, as well as the potential mechanisms of action, of Rhanterium epapposum essential oil (REE) and its main constituents against Giardia lamblia infection.
Methods: The analysis of REE was performed using the Gas Chromatography-Mass Spectrometry (GC-MS) detector. The in vitro effects of REE and its main constituents on viability of G.
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