Context: Tuberculosis (TB), though preventable and curable, remains a global health problem, ranked one of the top causes of death worldwide, despite the World Health Organization's strategies. This may be due to the stigma surrounding the disease.
Aim: This study assesses TB stigma in light of knowledge, attitudes, and preventive practices among individuals in an urban community.
Settings And Design: This was a descriptive, cross-sectional study among 317 residents of Surulere, Lagos, Nigeria, selected by multi-stage sampling.
Subjects And Methods: Data were collected using a pretested, semi-structured, interviewer-administered questionnaire and analyzed using Epi InfoTM version 7.2.2.6 2018 (Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA).
Statistical Analysis Used: Descriptive variables were summarized as frequencies, and the Chi-square test was used to test the associations. The level of significance was predetermined at P ≤0.05.
Results: Most participants were between the age group of 21 and 40 years. Approximately 9 out of every 10 respondents (91.8%) were aware of TB. Overall, only 2.4% of respondents had good knowledge of TB, more than half (59.1%) had positive attitudes toward TB, about one-third (37.1%) had good preventive practices and 22.7% of respondents expressed TB stigma, 63.6% would show no compassion or desire to help people with TB while 64.3% would rather people with TB were never employed. However, good knowledge translated into less stigma (P <0.001).
Conclusions: Most participants were aware of TB, although knowledge, attitude, and practice levels were poor. Knowledge was found to reduce TB stigma, reinforcing the need for improved community literacy regrading TB. This has the potential to influence health-seeking behavior and promote better TB prevention, detection, and treatment outcomes.
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http://dx.doi.org/10.4103/aam.aam_40_20 | DOI Listing |
Curr Rheumatol Rev
January 2025
University of Toronto, Psoriatic Arthritis Program, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada.
Psoriatic arthritis (PsA) is a heterogeneous inflammatory disease with various joint and skin manifestations and multiple associated comorbidities. The management of PsA is important not only in controlling disease activity and preventing subsequent damage but also in improving the quality of life and reducing mortality. Over the years, numerous drugs have been introduced into the therapeutic armamentarium of the disease.
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January 2025
Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Background: The Australian Rheumatology Association identified the use of imaging in patients with low back pain without indication of serious pathology as a low-value practice.
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Methods: We conducted a retrospective review of all adult patients (18 years and older) who presented with low back pain to the Fiona Stanley Hospital emergency department from 1 July 2020 to 31 December 2020.
Probiotics Antimicrob Proteins
January 2025
Department of Reproductive Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, China.
Probiotics exert a diverse range of immunomodulatory effects on the human gut immune system. These mechanisms encompass strengthening the intestinal mucosal barrier, inhibiting pathogen adhesion and colonization, stimulating immune modulation, and fostering the production of beneficial substances. As a result, probiotics hold significant potential in the prevention and treatment of various conditions, including inflammatory bowel disease and colorectal cancer.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Hannover Medical School, Institute of Pharmacology, D-30625, Hannover, Germany.
The increasing supply shortages of antibacterial drugs presents significant challenges to public health in Germany. This study aims to predict the future consumption of the ten most prescribed antibacterial drugs in Germany up to 2040 using ARIMA (Auto Regressive Integrated Moving Average) models, based on historical prescription data. This analysis also evaluates the plausibility of the forecasts.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Tsinghua University, Tsinghua Shenzhen International Graduate School, CHINA.
The crosstalk of transition metal ions between the metal oxide cathode and Zn anode restricts the practical applications of aqueous zinc-ion batteries (ZIBs). Herein, we propose a decoupled electrolyte (DCE) consisting of a nonaqueous-phase (N-phase) anolyte and an aqueous-phase (A-phase) catholyte to prevent the crosstalk of Mn2+, thus extending the lifespan of MnO2-based ZIBs. Experimental measurements and theoretical modelling verify that trimethyl phosphate (TMP) not only synergistically works with NH4Cl in the N-phase anolyte to enable fast Zn2+ conduction while block Mn2+ diffusion toward anode, but also modifies the Zn2+ solvation structure to suppress the dendrite formation and corrosion on Zn anode.
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