AI Article Synopsis
- The study evaluated the eosinophil/monocyte ratio (EMR) as a potential predictor for the prognosis of patients suffering from decompensated heart failure (HF).
- The research included a total of 1,883 adults diagnosed with decompensated HF, divided into three groups based on EMR levels, and findings showed varying rates of cardiovascular death or HF rehospitalization among these groups.
- Results indicated a significant correlation between lower EMR levels and higher risks of adverse outcomes, suggesting that EMR could be a useful measure for assessing prognosis in such patients.
Article Abstract
Purpose: The aim of this study was to assess the value of the eosinophil/monocyte ratio (EMR) for predicting the prognosis of decompensated heart failure (HF).
Patients And Methods: This was a retrospective cohort study. We included adults (≥18 years old) diagnosed with decompensated HF for whom EMR data were available. The patients were divided into three groups according to EMR tertiles (T1 [EMR≤0.15], T2 [0.15
Results: Initially, the records of 2264 patients with decompensated HF were screened; 1883 of these patients had EMR data and were therefore included in the study. There were 627 patients in the T1 group, 628 in the T2 group, and 628 in the T3 group. The risk of cardiovascular death or HF rehospitalization was significantly different among the three groups (Log rank test, P=0.007). Compared with the T3 group, both the T1 group (hazard ratio [HR]: 1.50, 95% confidence interval [CI]: 1.16-1.94, P=0.002) and the T2 group (HR: 1.34, 95% CI: 1.03-1.74, P=0.030) had significantly higher rates of cardiovascular death or HF rehospitalization. A Cochran-Armitage test for trend showed a positive correlation between the EMR and the composite outcome of cardiovascular death or HF. There was a significant difference between the three groups in terms of cardiovascular death (Log rank test, P<0.001) and HF rehospitalization (Log rank test, P=0.03).
Conclusion: The EMR is positively correlated with the risk of cardiovascular death or HF rehospitalization in patients with decompensated HF. Specifically, the lower the EMR, the higher the risk of cardiovascular death or HF rehospitalization.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453176 | PMC |
| http://dx.doi.org/10.2147/JIR.S325229 | DOI Listing |
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