Despite higher incidence of patellofemoral pain (PFP) and consequently morbidity, the understanding about PF factors leading to PF arthritis is way lacking. A prospective study of first 80 patients who were diagnosed with chondromalacia patella (CMP) on magnetic resonance imaging (MRI) divided into early and late CMP groups were evaluated clinically, radiologically, and in terms of functional outcome. : Quadriceps angle, Clark's test, and Insall-Salvati ratio results were nonsignificant despite greater values were observed in late CMP group, whereas trochlear morphology results (sulcus angle: 153:138 degrees and sulcus depth 3.9:5.4 mm) and clinical scores were significant in late CMP group (Kujala's score: 61:78, whereas PF pain score: 43:25). Type-C patellar morphology was found in greater number in late CMP cohort. Trochlear and patellar morphologies along with clinical scores play a key role in understanding of the CMP.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448244 | PMC |
http://dx.doi.org/10.1055/s-0041-1734361 | DOI Listing |
Inflammation
September 2024
Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA.
Neutrophils, polymorphonuclear leukocytes (PMN), express numerous pattern recognition receptors, including TLRs, capable of recognizing a wide variety of pathogens. Receptor engagement initiates a cascade of PMN responses with some occurring in seconds, and some requiring de novo protein synthesis over the course of many hours. Although numerous species of bacteria and bacterial products have been shown to activate PMN via TLRs, the signaling intermediates required for distinct PMN responses have not been well-defined in human PMN.
View Article and Find Full Text PDFFront Cardiovasc Med
February 2024
Cardiolology Dept., Hospital Universitario Puerta de Hierro, Madrid, Spain.
Introduction: We conducted a study to determine the prevalence of structural heart disease in patients with CF, the characteristics of a cardiomyopathy not previously described in this population, and its possible relationship with nutritional deficiencies in CF.
Methods: We studied 3 CMP CF patients referred for heart-lung transplantation and a prospective series of 120 adult CF patients. All patients underwent a clinical examination, blood tests including levels of vitamins and trace elements, and echocardiography with evaluation of myocardial strain.
RSC Adv
February 2024
Department of Chemistry, CMP Degree College, University of Allahabad Prayagraj 211002 Uttar Pradesh India
[This corrects the article DOI: 10.1039/D3RA01364B.].
View Article and Find Full Text PDFOncol Rep
February 2024
Department of Basic Sciences, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL 33431‑0991, USA.
medRxiv
November 2023
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN.
Background: Cardiomyopathy (CMP) is the leading cause of death in Duchenne muscular dystrophy (DMD). Characterization of disease trajectory can be challenging, especially in the early stage of CMP where onset and clinical progression may vary. Traditional metrics from cardiovascular magnetic resonance (CMR) imaging such as LVEF (left ventricular ejection fraction) and LGE (late gadolinium enhancement) are often insufficient for assessing disease trajectory.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!