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Article Synopsis
  • A 46-year-old man developed painful, reddish skin lesions on both cheeks that progressed to larger, vegetative plaques and caused scarring.
  • The second lesion was painful, had a high pain score, and showed signs of inflammation with a histopathology revealing a neutrophil-rich condition.
  • Treatment with high doses of corticosteroids led to significant improvement, indicating the diagnosis of vegetative pyoderma gangrenosum, highlighting that not all skin infections are actually infectious.
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Article Synopsis
  • Pyoderma gangrenosum (PG) is an inflammatory skin condition that leads to painful, quickly developing ulcers and is often misdiagnosed due to its resemblance to other health issues; this study focused on its clinicopathologic characteristics and underlying conditions among patients in the Indian subcontinent.
  • Over a ten-year period, the study identified 17 patients diagnosed with PG, predominantly affecting individuals in their early 30s, with ulcerative variants being most common; nearly a third had systemic associations with autoinflammatory syndromes.
  • Treatments typically included systemic steroids and alternative medications, with more than half of the patients achieving remission within 2 to 3 months; however, there were
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Crusted plaques on the face.

Int J Dermatol

December 2024

Dermatology Department, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.

Article Synopsis
  • - Facial neutrophilic dermatosis is a rare skin condition recently identified, characterized by crusty lesions resembling pyoderma gangrenosum, but with limited involvement of the facial area.
  • - There is some debate among experts regarding its classification, with some considering it a variant of Sweet's syndrome and others treating it as a distinct entity.
  • - Recent cases, including the one discussed, have noted potential links between facial neutrophilic dermatosis and conditions like ulcerative colitis, suggesting diverse clinical presentations.
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Background In the pediatric population, acute post-streptococcal glomerulonephritis (PSGN) is a common glomerular etiology of hematuria and acute hypertension leading to hospitalization. We conducted this study to know the clinical profile and occurrence of acute PSGN in patients presenting with features of acute nephritic syndrome. Methods This prospective observational study was conducted on children aged between two and 18 years, presenting with clinical features of acute glomerular nephritis (AGN).

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Article Synopsis
  • Hyperbaric oxygen (HBO) therapy is gaining attention for treating conditions beyond its established uses, particularly due to its effects on hypoxia and inflammation.
  • A web-based International Multicenter Registry collects data from various centers to analyze HBO treatment outcomes and identify new potential applications across different medical specialties.
  • The study found that out of 9,726 patients, 378 were treated for 45 new indications, with a significant number related to post-COVID-19 conditions, ulcerative colitis, and Crohn's disease.
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