Background And Purpose: , as a new characterized pathogenic yeast, has attracted remarkable attention in the recent decade due to its rapid global emergence and multidrug resistance traits. This unique species is able to cause nosocomial outbreaks and tolerate adverse conditions; however, it has been mostly misidentified by conventional methods.
Case Report: This report aimed to describe the first fluconazole-resistant case of otitis in an immunocompetent patient in Iran. The isolate showed minimum inhibitory concentration of ≥ 32 μg/ml for fluconazole; however, the patient was treated with topical clotrimazole and miconazole with no recurrence.
Conclusion: This was the second strain of isolated from otitis in Iran which was fluconazole-resistant, unlike the first Iranian isolate.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443880 | PMC |
http://dx.doi.org/10.18502/cmm.7.1.6243 | DOI Listing |
Iran J Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Egypt.
Introduction: Scleroma is a chronic, specific granulomatous disease that affects the head and neck mucosa. Its common sites are the nose and larynx; however, it might affect other areas. One of the rare sites to be affected is the middle ear and mastoid cavity, for which the term otoscleroma was coined.
View Article and Find Full Text PDFAcute necrotizing otitis media is a severe middle ear infection which causes necrosis of the tympanic cavity. A 54-year-old female was presented who suffered from diabetes mellitus and end-stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa. She rapidly progressed to total necrosis of the tympanic membrane.
View Article and Find Full Text PDFActa Otolaryngol
December 2024
Department of 'Organi di Senso', University "Sapienza", Rome, Italy.
Background: endoscopic ear surgery in patients Chronic Otitis Media(COM) media with eardrum atelectasis.
Objective: to compare the postoperative outcomes and audiological results of the endoscopic approach versus the microscopic approach for treatment of COM media with eardrum atelectasis, using a randomized prospective model.
Methods: Sixty patients were consecutively enrolled in the study and randomized into two groups: Group A 32 patients underwent canal wall up tympanoplasty (CWA); Group B 28 patients underwent tympanoplasty with an exclusive trans-meatal endoscopic approach.
Indian J Otolaryngol Head Neck Surg
December 2024
Clinical research development unit of Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC Neurol
November 2024
Clinical Research Development Unit, Faculty of Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Infectious brain abscesses and granulomas, characterized by localized collections of pus or inflammatory tissue within the brain parenchyma, pose significant clinical challenges due to their potentially life-threatening nature and complex management requirements.
Methods: This cross-sectional study investigated patients diagnosed with infectious brain abscesses and granulomas from March 1, 2012, to October 22, 2021, in Mashhad, Iran. Data were collected from adult patients admitted to the two primary referral centers for community-acquired neuroinfections and neuroinflammations.
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