Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441209 | PMC |
| http://dx.doi.org/10.1016/j.hrcr.2021.06.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lophine incorporated azo dye as a novel colorimetric sensor for multiple metal ions.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Laboratory of Organic Chemistry, Tarsadia Institute of Chemical Science, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli-Mahuva Road, Tarsadi 394650 Surat Gujarat India. Electronic address:
A single molecule sensor for several analytes is indeed desired by the scientists around the world due to obvious advantages. In this report we present a new class of Lophine incorporated azo dyes that has capacity of differential colorimetric detection of several metal ions. Interestingly the sensor was found to have pH dependent selective response towards several metals.
View Article and Find Full Text PDFA review of cutting-edge biomarkers for diagnosing coronary artery disease.
Medicine (Baltimore)
January 2025
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Chronic coronary artery disease (CAD) remains a significant global healthcare burden. Current risk assessment methods have notable limitations in early detection and risk stratification. Hence, there is an urgent need for innovative biomarkers that facilitate the premature CAD diagnosis, ultimately leading to reduction in associated morbidity and mortality rates.
View Article and Find Full Text PDFAmphibian-Derived Peptides as Natural Inhibitors of SARS-CoV-2 Main Protease (Mpro): A Combined In Vitro and In Silico Approach.
Chem Biodivers
January 2025
Universidad Nacional del Litoral Facultad de Bioquimica y Ciencias Biologicas, Química Orgánica, Ciudad Universitaria. Paraje el Pozo S/N, Argentina, 3000, Santa Fe, ARGENTINA.
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has highlighted the urgent need for novel therapeutic agents targeting viral enzymes such as the main protease (Mpro), which plays a crucial role in viral replication. In this study, we investigate the inhibitory potential of 23 peptides isolated from the skin of amphibians belonging to the Hylidae and Leptodactylidae families against SARS-CoV-2 Mpro. Five peptides demonstrated significant inhibition using a colorimetric Mpro inhibition assay, with IC50 values ranging from 41 to 203 µM.
View Article and Find Full Text PDFUnderstanding the Myelin Ratio from First Principles, Its Derivation, Uses and Artifacts.
ASN Neuro
January 2025
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA.
In light of the increasing importance for measuring myelin ratios - the ratio of axon-to-fiber (axon + myelin) diameters in myelin internodes - to understand normal physiology, disease states, repair mechanisms and myelin plasticity, there is urgent need to minimize processing and statistical artifacts in current methodologies. Many contemporary studies fall prey to a variety of artifacts, reducing study outcome robustness and slowing development of novel therapeutics. Underlying causes stem from a lack of understanding of the myelin ratio, which has persisted more than a century.
View Article and Find Full Text PDFAutomated mold defects classification in paintings: A comparison of machine learning and rule-based techniques.
PLoS One
January 2025
Faculty of Science and Engineering, School of Computer Science, University of Hull, Hull, United Kingdom.
Mold defects pose a significant risk to the preservation of valuable fine art paintings, typically arising from fungal growth in humid environments. This paper presents a novel approach for detecting and categorizing mold defects in fine art paintings. The technique leverages a feature extraction method called Derivative Level Thresholding to pinpoint suspicious regions within an image.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!