Given high COVID-19 infection and mortality ratesamong racial minorities in the US and their higher rates of religiosity, it is important to examine how the intersection of race and religion influences perceptions of COVID-19 vaccinations.Data for this study come from online surveys conducted in twelve congregations between October and December 2020 (N = 1,609). Based on logistic regression analyses, this study demonstrates a severe disparity of 24 percentage points (95% confidence interval 0.14-0.33) in anticipated COVID-19 vaccine acceptance between African Americans and White Americans, even when controlling for trust in COVID-19 information from scientists and levels of worrying about COVID-19 as well as religiosity and demographic factors. Religiosity is negatively associated with COVID-19 vaccine acceptance across racial groups. The findings suggest that the intersection of race and religion should be considered when designing immunization programs, for instance by fostering collaborations and dialogue with faith leaders of racial minority congregations.
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http://dx.doi.org/10.1016/j.vaccine.2021.09.005 | DOI Listing |
Braz J Microbiol
January 2025
Center of Technological Development, Biotechnology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Adjuvants are crucial for maintaining specific, protective, and long-lasting immunity. Here, we aimed to evaluate the antigenic and immunogenic activity of a recombinant form of the S1 domain of the Spike protein, associated with biogenic silver nanoparticles (bio-AgNP) and Alhydrogel as an alternative and conventional adjuvant, respectively, for a SARS-CoV-2 subunit vaccine. We produced and evaluated the antigenicity of the recombinant S1 (rS1) protein by testing its recognition by antibodies present in SARS-CoV-2 positive human serum.
View Article and Find Full Text PDFJ R Soc Interface
January 2025
Department of Mathematics, The University of Manchester, Manchester, UK.
The reproduction number, the mean number of secondary cases infected by each primary case, gives an indication of the effort required to control the disease. Beyond the well-known reproduction number, there are two natural extensions, namely the and reproduction numbers. As behaviour, population immunity and viral characteristics can change with time, these reproduction numbers can vary over time.
View Article and Find Full Text PDFNiger Med J
January 2025
Department of Community Medicine, University of Jos, Jos, Plateau State, Nigeria.
Background: COVID-19 vaccination is crucial to containing the pandemic. COVID-19 vaccine knowledge, attitudes, and uptake among medical students are vital, as they are future healthcare professionals expected to promote vaccination. This study assessed the knowledge of the COVID-19 vaccine, its uptake, and associated factors among medical students.
View Article and Find Full Text PDFFront Immunol
January 2025
Institute of Virology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Background: The emergence of novel SARS-CoV-2 variants challenges immunity, particularly among immunocompromised kidney transplant recipients (KTRs). To address this, vaccines have been adjusted to circulating variants. Despite intensive vaccination efforts, SARS-CoV-2 infections surged among KTRs during the Omicron wave, enabling a direct comparison of variant-specific immunity following-vaccination against Omicron BA.
View Article and Find Full Text PDFFront Immunol
January 2025
Axe de Recherche Maladies Infectieuses et Immunitaires, Centre de Recherche du CHU de Québec-Université Laval, Quebec City, QC, Canada.
Introduction: The innate immune response is an important first checkpoint in the evolution of an infection. Although adaptive immunity is generally considered the immune component that retains antigenic memory, innate immune responses can also be affected by previous stimulations. This study evaluated the impact of vaccination on innate cell activation by TLR7/8 agonist R848, as well as seasonal variations.
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