The antituberculosis drug telacebec is ineffective against Mycobacterium abscessus. A recent study suggested that TB47, a telacebec analogue, potentiated the efficacy of clofazimine against M. abscessus. Here, we report that TB47 not only is ineffective against M. abscessus but also does not potentiate the activity of clofazimine.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597762 | PMC |
| http://dx.doi.org/10.1128/AAC.00964-21 | DOI Listing |
Publication Analysis
Top Keywords
tb47 telacebec
8
potentiate activity
8
activity clofazimine
8
mycobacterium abscessus
8
qcrb inhibitors
4
inhibitors tb47
4
telacebec potentiate
4
clofazimine mycobacterium
4
abscessus
4
abscessus antituberculosis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!