Two new diterpenoids, including a -isopimarane type (1) and an abietane type (2), were isolated from sp. (71-10-1-1). Their structures, including absolute configurations, were elucidated by NMR spectroscopic analyses, X-ray crystallography, C chemical shifts calculations, and ECD calculations. This is the first report of diterpenoids from sp. Furthermore, short-term memory enhancement against Alzheimer's disease (AD), anti-inflammatory, and cytotoxic activities of 1-2 were also evaluated. The results showed that compound 1 exhibited short-term memory enhancement activity against AD.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440928 | PMC |
| http://dx.doi.org/10.3389/fchem.2021.749272 | DOI Listing |
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