Kawasaki disease (KD), particularly incomplete form, might present with wide spectrum clinical features. The treatment regimen includes a combination of intravenous immunoglobulins (IVIG) and aspirin. The use of steroids has been studied as an adjunctive therapy and its role in preventing coronary artery (CA) complications is still debatable. Here, we are presenting a rare presentation of incomplete KD. A previously healthy 5-year-old Arab girl, presented with clinical features consistent with pneumonia, rash, and enlarged cervical lymph nodes. On admission, antibiotics were administered intravenously in addition to steroids considering her reactive airway disease history which resulted in interim improvement. Yet, upon clinical worsening, her clinical status was revised, laboratory and physical examination revealed raised inflammatory markers, new opacity of pulmonary consolidation on chest X-ray, and peeling of skin. Because of high clinical suspicion of incomplete KD combined with her echocardiography that showed prominent coronary arteries, diagnosis of incomplete KD was made. After treating her with IVIG and aspirin, the patient made a full recovery. We are reporting pneumonia-like presentation of incomplete KD. High index of suspicion is required to diagnosis and treat promptly to prevent complications.
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http://dx.doi.org/10.7759/cureus.17280 | DOI Listing |
J Biol Chem
January 2025
Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903. Electronic address:
The mitochondrial Ca uniporter is the Ca channel responsible for mitochondrial Ca uptake. It plays crucial physiological roles in regulating oxidative phosphorylation, intracellular Ca signaling, and cell death. The uniporter contains the pore-forming MCU subunit, the auxiliary EMRE protein, and the regulatory MICU1 subunit, which blocks the MCU pore under resting cellular Ca concentrations.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, Banacha 1a Str., 02-097 Warsaw, Poland.
: The aim was to evaluate vestibular function in patients with unilateral vestibular schwannoma before and in the short and medium term after surgical treatment to analyze vestibular compensation. The identification of the prognostic factors determining incomplete and slower balance recovery was assessed. Forty-five patients with unilateral vestibular schwannoma treated surgically through the middle cranial fossa and translabyrinthine approach were enrolled in this study.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Obstetrics and Gynaecology, Croydon University Hospital, Croydon CR7 7YE, UK.
The aim of this study is to validate a uniform method for measuring perineal descent which can be used for different imaging methods, to establish cut-off values for this measurement, and to assess diagnostic test accuracy (DTA) of imaging techniques using these cut-off values. Secondly, the study aims to correlate perineal descent to symptoms, signs and imaging findings in women with obstructed defaecation syndrome (ODS) to assess its clinical relevance. Cross-sectional study of 131 women with symptoms of ODS.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Medical Specialties I, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Purpose: is the main etiologic agent implicated in primary amoebic meningoencephalitis (PAM). It is also known as the brain-eating amoeba because of the severe brain inflammation following infection, with a survival rate of about 5%. This review aims to identify infections and evaluate patients' progression.
View Article and Find Full Text PDFInsects
January 2025
Yunnan Provincial Engineering and Research Center for Sustainable Utilization of Honeybee Resources, Eastern Bee Research Institute, College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Italian honey bees (IHBs, ) exhibit superior comb-building abilities compared with Chinese honey bees (CHBs, ), which often fail to fully utilize wax foundations, resulting in incomplete comb structures. The present study aimed to accelerate comb construction in CHB colonies using IHBs. In the experiment, IHB colonies, each with approximately 42,000 adult workers, required over four hours to construct a semi-drawn comb on CHB wax foundations.
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