AI Article Synopsis

  • Paraganglioma of the urinary bladder is a rare tumor that can either secrete hormones (functional) or not (nonfunctional), and it can be mistaken for a more common bladder cancer, urothelial carcinoma.
  • A case involving a 78-year-old man with blood in his urine was initially thought to be urothelial carcinoma based on medical imaging, but was ultimately diagnosed as paraganglioma through detailed examination and specific lab testing.
  • The study emphasizes the importance of careful diagnosis by medical professionals and notes the need for long-term follow-up for patients with this type of tumor.

Article Abstract

Paraganglioma of the urinary bladder is a rare neoplasm. It may be functional, secreting catecholamines, or nonfunctional. Clinically and histopathologically, it has the potential to be misdiagnosed as a more common urothelial carcinoma, especially in nonfunctional cases. A high index of suspicion on the part of pathologist can help in identification of characteristic histopathologic feature which coupled with immunohistochemistry can help in establishing the correct diagnosis. We present a case of paraganglioma in a 78-year-old male patient presenting with haematuria. Clinical provisional diagnosis rendered based on cystoscopic findings and radiology was urothelial carcinoma; however, was confirmed to be a case of paraganglioma of bladder on histopathological and immunohistochemical evaluation. A long follow-up is warranted. Herein, we also briefly review the relevant literature.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448256PMC
http://dx.doi.org/10.7759/cureus.17265DOI Listing

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