The present preliminary study aims to evaluate the possible positive outcomes of ultrasonography-guided sialolithotomies and duct stricture dilations utilizing stone retrieval baskets and guide wires. A total of 6 cases in an ongoing study (4 cases of sialolithiasis and 2 cases of duct strictures with intraluminal adhesion) were analyzed. All sialoliths were <5 mm in diameter. Stone removals and duct dilations were performed under ultrasonography guidance with two different types of linear probes. Edema measurements were carried out, and the area of edema was evaluated via the echogenicity changes. Patient satisfaction was also evaluated by the patients themselves using a Visual Analog Scale questionnaire on postoperative day 0, and on days 1, 2, and 3. There were no postoperative complications, and mouth openings returned to normal at 7-day follow-up. The pain scores decreased after 6 hours, and pain subsided completely after 12 hours in all the patients. Edema also resolved gradually after the operation. The patient satisfaction levels were high.
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http://dx.doi.org/10.15557/JoU.2021.0038 | DOI Listing |
World J Gastrointest Surg
January 2025
Department of Emergency Medicine, Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, Guangdong Province, China.
Background: Hepatobiliary stone disease involves an intrahepatic bile duct stone that occurs above the confluence of the right and left hepatic ducts. One-step percutaneous transhepatic cholangioscopic lithotripsy (PTCSL) using the percutaneous transhepatic one-step biliary fistulation (PTOBF) technique enables the clearing of intrahepatic stones and the resolution of strictures. However, hepatolithiasis with associated strictures still has high residual and recurrence rates after one-step PTCSL.
View Article and Find Full Text PDFCureus
December 2024
Paediatric Surgery, Bristol Royal Hospital for Children, Bristol, GBR.
Introduction: Management of urethral trauma lacks clarity in the paediatric population. There is no clear guidance for management and follow-up of these patients which can lead to missing the long-term sequelae of the primary injury. Catheter-associated urethral injuries are less likely to cause a complete transaction of the urethra.
View Article and Find Full Text PDFAME Case Rep
October 2024
Department of Internal Medicine, Unity Hospital, Rochester, NY, USA.
Background: Surgical clip migration is a rare complication that can happen many years following a successful cholecystectomy. It has a similar clinical presentation as choledocholithiasis. The diagnosis is usually made using imaging modalities such as ultrasounds, computed tomography (CT) scans, or magnetic resonance cholangiopancreatography (MRCP).
View Article and Find Full Text PDFClin Transl Gastroenterol
January 2025
Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA.
Introduction: We assessed potential mechanisms behind the requirement for more frequent dupilumab dosing in eosinophilic esophagitis (EoE) compared with other approved indications.
Methods: Results for the phase 3 LIBERTY EoE TREET study coprimary endpoints (proportion of patients achieving a peak intraepithelial eosinophil count of ≤6 eosinophils per high-power field and absolute change from baseline in Dysphagia Symptom Questionnaire total score) were pooled in exposure-response analyses.
Results: A steep initial relationship then plateau was observed between higher dupilumab steady-state trough concentrations and decreased eosinophilic infiltration at week 24, whereas a graded exposure-response relationship was observed for symptomatic improvement at week 24.
Ther Adv Urol
January 2025
UT Southwestern Department of Urology, Dallas, TX, USA.
Background: The Optilume paclitaxel drug-coated balloon (DCB) is a relatively new-to-market alternative in the management of male anterior urethral stricture disease. The pivotal trial excluded patients with a history of urethroplasty, although these strictures may be amenable to endoscopic management. Therefore, we sought to assess the efficacy of the DCB in the management of recurrent strictures following urethroplasty.
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