AI Article Synopsis
- - Daidzein is a phytoestrogen found in soybeans that mimics mammalian estrogens and can influence estrogen-related diseases like breast cancer and osteoporosis.
- - In addition to its estrogen-related benefits, daidzein also acts as an antioxidant and anti-inflammatory agent, which may contribute to its potential anticancer properties.
- - This review focuses on the pharmacodynamics of daidzein and its implications for human health, especially in alleviating postmenopausal symptoms and offering anti-aging benefits.
Article Abstract
Daidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and estrogen receptor (ER) complex. Hence, daidzein puts forth shielding effects against a great number of diseases, especially those associated with the control of estrogen, such as breast cancer, diabetes, osteoporosis, and cardiovascular disease. However, daidzein also has other ER-independent biological activities, such as oxidative damage reduction acting as an antioxidant, immune regulator as an anti-inflammatory agent, and apoptosis regulation, directly linked to its potential anticancer effects. In this sense, the present review is aimed at providing a deepen analysis of daidzein pharmacodynamics and its implications in human health, from its best-known effects alleviating postmenopausal symptoms to its potential anticancer and antiaging properties.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448605 | PMC |
| http://dx.doi.org/10.1155/2021/6331630 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!