Background: L. () is a medicinal and aromatic plant belonging to the family Asteraceae that is more widespread in the folded Middle Atlas Mountains, Morocco.
Materials And Methods: This study was run to investigate the phytochemical composition and antioxidant, antibacterial, and antifungal activities of L. essential oil. This oil was extracted from the fresh plant material by using the Clevenger apparatus. The phytochemical composition was characterized by GC-MS. The antioxidant activity was evaluated using different methods including DPPH, -carotene bleaching, and total antioxidant capacity. The antibacterial activity was tested vs. multidrug-resistant bacteria including both Gram-negative and Gram-positive using inhibition zones in agar media and minimum inhibitory concentration (MIC) bioassays. The antifungal activity was conducted on , , and using a solid medium assay.
Results: The chromatographic characterization of essential oils of revealed the presence of 34 compounds constituting 99.91% of the total essential oil. The latter was found to have promising antioxidant activity by all bioassays used such as DPPH, carotene bleaching, and total antioxidant capacity. The results obtained showed that our plant oils had potent antibacterial activity towards Gram-negative ( 57, 97, , and and Gram-positive (), so that the maximum inhibition zones and MIC values were around 18-37 mm and 3.25 to 12.5 mg/mL, respectively. The oil also showed antifungal activity towards , and except for flavus species.
Conclusion: The findings obtained in the work showed that can serve as a valuable source of natural compounds that can be used as a new weapon to fight radical damage and resistant microbes.
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| http://dx.doi.org/10.1155/2021/5902851 | DOI Listing |
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