Wood-based products can contribute to climate change mitigation by prolonging the storage of carbon in the anthroposphere. In Indonesia, however, many wood-based products originate from unsustainable sources due to widespread land-use changes over the past decades. To reconcile economic development and climate policy, a detailed and comprehensive carbon life cycle assessment is needed, covering biospheric and technospheric woody carbon flows and emissions over time. In this study, we combine dynamic material flow analysis, stock modeling, and life cycle assessment to estimate life cycle carbon emissions over time of wood products from different land conversion types in Indonesia on a hectare (ha) basis. Wood production from clear-cut primary forest conversions to oil palm, secondary forest, and timber plantations lead to net carbon emissions between 1206-1282, 436-449, and 629-958 t-CO-eq/ha, respectively, at the end of the 200-year time horizon (TH). The counter-use scenarios of using non-renewable materials or energy instead of wood-based products for the same set of scenarios while leaving primary forests untouched display 44-57, 59-88, and 5-48% lower global warming potentials, respectively, at the end of the TH. Wood products from forest plantations on restored degraded land (DL_FP), reduced-impact logging (RIL), and improved reduced-impact logging (RIL-C) of primary forest went beyond carbon neutrality, displaying carbon removal potentials of up to around -218, -378, and -739 t-CO-eq/ha, respectively, by year 200. At the one ha-scale, our results indicate that keeping primary forests intact is the climate-preferable option, even when emissions from the counter-use of non-renewable materials or energy are factored in, except if RIL is performed. Therefore, wood product utilization would only be favorable from a climate perspective in DL_FP or RIL pathways. These results help screen different land conversion policy options and providing information about the climate mitigation potential of wood products in different supply chains.
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http://dx.doi.org/10.1016/j.scitotenv.2021.150226 | DOI Listing |
Front Oncol
January 2025
Department of Anesthesiology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Totally implantable venous access port (TIVAP), a novel intravenous infusion system that is used for long-term intravenous treatment, has become increasingly popular among cancer patients undergoing chemotherapy and other patients requiring long-term intravenous infusions. This technology has been introduced into clinical practice in China, with successful results. Nevertheless, there are still certain problems; for instance, China has not set up a specialized regulatory agency to oversee research and set guidelines for the comprehensive life-cycle management of TIVAP.
View Article and Find Full Text PDFBMJ Oncol
November 2024
Department of Computer Science, Durham University, Durham, UK.
Objectives: Routine monitoring of renal and hepatic function during chemotherapy ensures that treatment-related organ damage has not occurred and clearance of subsequent treatment is not hindered; however, frequency and timing are not optimal. Model bias and data heterogeneity concerns have hampered the ability of machine learning (ML) to be deployed into clinical practice. This study aims to develop models that could support individualised decisions on the timing of renal and hepatic monitoring while exploring the effect of data shift on model performance.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
Background: Knee Osteoarthritis (KOA) is a prevalent condition worldwide, significantly diminishing quality of life and productivity. Except for the alignment change, muscle activation patterns (MAP) have garnered increasing attention as another crucial factor contributing to KOA.
Objective: This study explores the factors, characteristics, and effects of MAP changes caused by KOA, providing a neuromuscular-based causal analysis for the rehabilitation treatment of KOA.
BMC Plant Biol
January 2025
Institute of Biology, Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, Neuchâtel, Switzerland.
Background: Upland cotton (Gossypium hirsutum) plants constitutively store volatile terpenes in their leaves, which are steadily emitted at low levels. Herbivory leads to a greater release of these stored volatiles. Additionally, damaged plants increase the accumulation of volatile terpenes in their leaves and begin to synthesize and emit other terpenes and additional compounds.
View Article and Find Full Text PDFNat Cancer
January 2025
Department of Oncological Sciences, Precision Immunology Institute, the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cyclin-dependent kinases (CDKs) 4 and 6 (CDK4/6) are important regulators of the cell cycle. Selective CDK4/6 small-molecule inhibitors have shown clinical activity in hormonal receptor-positive (HR) metastatic breast cancer, but their effectiveness remains limited in other cancer types. CDK4/6 degradation and improved selectivity across CDK paralogs are approaches that could expand the effectiveness of CDK4/6 targeting.
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