The study investigated the potential relationships between air pollution, socio-economy, and proven pathologies (e.g., respiratory, cardiovascular) within an industrial area in Southern France (Etang de Berre), gathering steel industries, oil refineries, shipping, road traffic and experiencing a Mediterranean climate. A total of 178 variables were simultaneously integrated within a Bayesian model at intra-urban scale. Various unsupervised and supervised algorithms (maximum spanning tree, tree-augmented naive classifier) as well as sensitivity analyses were used to better understand the links between all variables, and highlighted correlations between population exposure to air pollutants and some pathologies. Adverse health effects (bronchus and lung cancers for 15-65 years old people) were observed for hydrofluoric acid at low background concentration (<0.003 μg m) while exposure to particulate cadmium (0.210-0.250 μg m) disrupts insulin metabolism for people over 65 years-old leading to diabetes. Bronchus and lung cancers for people over 65 years-old occurred at low background SO concentration (6 μg m) below European limit values. When benzo[k]fluoranthene exceeded 0.672 μg m, we observed a high number of hospital admissions for respiratory diseases for 15-65 years-old people. The study also revealed the important influence of socio-economy (e.g., single-parent family, people with no qualification at 15 years-old) on pathologies (e.g., cardiovascular diseases). Finally, a diffuse polychlorinated biphenyl (PCB) pollution was observed in the study area and can potentially cause lung cancers.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.envres.2021.112059 | DOI Listing |
The analysis of complex mechanisms within population data, and within sub-populations, can be empowered by combining datasets, for example to gain more understanding of change processes of health-related behaviours. Because of the complexity of this kind of research, it is valuable to provide more specific guidelines for such analyses than given in standard data science methodologies. Thereto, we propose a generic procedure for applied data science research in which the data from multiple studies are included.
View Article and Find Full Text PDFPeerJ
January 2025
CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Universidade do Porto, Campus de Vairão, Porto, Portugal.
The rough pen shell Linnaeus, 1758 (family Pinnidae) is a mollusc with an Atlantic-Mediterranean distribution, typically inhabiting coarse sandy substrates. Habitat degradation is considered the primary cause of population decline, leading to the designation 'Vulnerable' in certain regions. In this study, we conducted a genetic analysis of populations of from Cabo Verde and compared them with populations from the Mediterranean and Macaronesia.
View Article and Find Full Text PDFTher Adv Drug Saf
January 2025
Department of Pharmacy, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing 400042, China.
Background: Gilteritinib and midostaurin are FLT3 inhibitors that have made significant progress in the treatment of acute myeloid leukemia. However, their real-world safety profile in a large sample population is incomplete.
Objectives: We aimed to provide a pharmacovigilance study of the adverse events (AEs) associated with gilteritinib and midostaurin through the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database.
Cogn Neurodyn
December 2025
Department of Physiology, School of Basic Medical Sciences, Chengdu Medical College, Sichuan, 610500 China.
Unlabelled: Parkinson's disease (PD) is a neurodegenerative disease with various clinical manifestations caused by multiple risk factors. However, the effect of different factors and relationships between different features related to PD and the extent of those factors leading to the incidence of PD remains unclear. we employed Bayesian network to construct a prediction model.
View Article and Find Full Text PDFAnn Med
December 2025
School of Special Education and Rehabilitation, BinZhou Medical University, Yantai, China.
Background: Individuals with alcohol use disorder (AUD) often experience symptoms such as anxiety, depression, and decreased sleep quality. Although these are not diagnostic criteria, they may increase dependence risk and complicate treatment. This study aims to analyze comorbidities and their complex relationships in AUD patients through epidemiological surveys and network analysis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!