AI Article Synopsis
- Scientists are studying a special type of DNA called ctDNA to learn more about cancer in Africa.
- They looked at blood samples from 15 patients with breast cancer at the time they were diagnosed.
- Most of the patients showed changes in their DNA that drive the cancer, which helps researchers understand the disease better.
Article Abstract
Circulating tumor DNA (ctDNA) sequencing studies could provide novel insights into the molecular pathology of cancer in sub-Saharan Africa. In 15 patient plasma samples collected at the time of diagnosis as part of the Ghana Breast Health Study and unselected for tumor grade and subtype, ctDNA was detected in a majority of patients based on whole- genome sequencing at high (30×) and low (0.1×) depths. Breast cancer driver copy number alterations were observed in the majority of patients.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448727 | PMC |
| http://dx.doi.org/10.1038/s41698-021-00219-7 | DOI Listing |
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