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Sarcoidosis and complications related to fillers have been reported following the COVID-19 vaccination. Additionally, cutaneous sarcoidosis has been observed around polymethyl methacrylate (PMMA) injection sites. Foreign-body reactions to PMMA can occur simultaneously with systemic sarcoidosis, suggesting a shared pathogenic mechanism between both conditions.

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Filler complications have a wide array of presentations including early and late manifestations. A rare late complication is the foreign body granuloma or granulomatous foreign body reaction. We present a case of giant foreign body granulomas developing 7 years after polymethylmethacrylate (PMMA) filler injection.

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Imaging Features and Complications of Facial Cosmetic Procedures.

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From the Department of Radiology, Head and Neck Section (A.M.S.d.S., M.D., C.A.F.C.N., M.d.O.S., L.G.P.D., S.A.S., J.D.Z., M.R.T.G.) and Neuroradiology Section (A.M.S.d.S.), Dasa/Alta Excelência Diagnóstica, Av Juruá 548, Alphaville, Barueri, São Paulo 06455-010 SP, Brazil; Department of Radiology, Neuroradiology Section, Irmandade da Santa Casa de Misericordia de Sao Paulo, São Paulo, Brazil (A.C.D., D.d.F.G.); Division of Head and Neck Imaging, Instituto Nacional do Cancer, Rio de Janeiro, Brazil (M.D.); Head and Neck Radiology Section, Universidade Federal de São Paulo, São Paulo, Brazil (S.A.S.); Head and Neck Radiology Section (S.A.S.) and Ultrasound Section (J.D.Z.), Universidade de São Paulo, São Paulo, Brazil; Department of Dermatology, Universidade de Brasília, Brasília, Brazil (L.F.S.); and Department of Radiology, ProScan Imaging, Cincinnati, Ohio (S.K.M.).

Facial aesthetic procedures have become increasingly popular and complex, making knowledge of facial anatomy crucial for achieving desired outcomes without complications. Some of the most common procedures include blepharoplasty, bichectomy, face-lifts, facial implants, thread lifting, and fillers. Blepharoplasty and bichectomy are surgical procedures that respectively aim to restore youthful contours to the periorbita and create a slimmer lower face by removing Bichat fat from the maxillofacial region.

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