Introduction: The diagnosis of temporal bone fractures (TBF) is based on radiological imaging. The most widely used classification divides fractures into longitudinal, transverse, and mixed. In recent years, other classifications have emerged to better predict clinical manifestations.
Objectives: To review computed tomography (CT) images of TBF, define their radiological pattern, and study the concordance of the observed findings with those described in the radiological report. To analyse the association between fracture types and clinical findings. To study the impact of mastoid pneumatization on fracture characteristics.
Methods: Retrospective study of 110 TBF diagnosed with CT between January 2016 and May 2019.
Results: Fifty-two transverse (47%), 34 longitudinal (30%), and 19 mixed fractures (17%) were identified with good interobserver agreement (k = .637). Longitudinal fractures were associated with conductive hearing loss (P < .001) and transverse fractures with sensorineural hearing loss (P = .005). Of the fractures, 8.2% showed involvement of the otic capsule, and were associated with sensorineural hearing loss (P < .001), facial paralysis (P = .019) and vertigo (P= .035). Fractures were more frequent in cases of greater pneumatization, and the involvement of the otic capsule in cases of very good pneumatization (P = .024).
Conclusions: The traditional classification of TBF is reproducible. Its association with clinical findings improves when the involvement of the otic capsule is also analysed. Mastoid pneumatization is not a protective factor for TBF or for involvement of the otic capsule.
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http://dx.doi.org/10.1016/j.otoeng.2020.09.003 | DOI Listing |
Vet Radiol Ultrasound
January 2025
Department of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Computed tomography is commonly used to evaluate feline otic disease; however, published studies characterizing the CT appearance of ear canal neoplasia are limited. The purpose of this multicenter, retrospective, secondary analysis, cross-sectional study was to describe the CT features of histopathologically confirmed feline ear canal neoplasia. The CT studies of 25 cats with ear canal neoplasia were prospectively scored by consensus of two veterinary radiologists.
View Article and Find Full Text PDFBiomedicines
October 2024
LBN, Laboratory of Bioengineering and Nanoscience, University of Montpellier, 34193 Montpellier, France.
Pluripotent stem cells (PSCs) offer many potential research and clinical benefits due to their ability to differentiate into nearly every cell type in the body. They are often used as model systems to study early stages of ontogenesis to better understand key developmental pathways, as well as for drug screening. However, in order to fully realise the potential of PSCs and their translational applications, a deeper understanding of developmental pathways, especially in humans, is required.
View Article and Find Full Text PDFSemin Ultrasound CT MR
October 2024
Neuroradiology Section, Department of Radiology, Hospital Sírio-Libanês, São Paulo, SP, Brazil; Neuroradiology Section, Instituto de Radiologia, Hospital das Clinicas da Universidade de Sao Paulo, Sao Paulo, SP, Brazil. Electronic address:
The intricate anatomy and embryology of the middle ear, labyrinth, and vertigo-related intracranial pathways involve complex developmental processes and contributions from multiple germ layers. The middle ear, comprised of the tympanic cavity, ossicles, and Eustachian tube, develops from the first and second branchial arches and clefts. In contrast, the inner ear originates from the otic vesicle, forming the bony and membranous labyrinths.
View Article and Find Full Text PDFRev Med Suisse
October 2024
Service d'ORL et de chirurgie cervicofaciale, Hôpitaux universitaires de Genève, 1211 Genève 14.
Dev Dyn
October 2024
Unidad de Excelencia, Instituto de Biomedicina y Genética Molecular de Valladolid (IBGM), Universidad de Valladolid y Consejo Superior de Investigaciones Científicas (CSIC), Valladolid, Spain.
Background: The mechanisms underlying the formation of complex structures such as during the outgrowth of the cochlear duct are still poorly understood.
Results: We have analyzed the morphological and molecular changes associated with cochlear development in mouse mutants for the transcription factor Meis2, which show defective coiling of the cochlea. These morphological abnormalities were accompanied by the formation of ectopic and extra rows of sensory hair cells.
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