Medical linear-accelerator-based stereotactic radiosurgery (SRS) using a stereotactic apparatus or image-guided radiotherapy system for intracranial lesions is performed widely in clinical practice. In general, Winston-Lutz (WL) tests using films or electric portal imaging devices (EPIDs) have been performed as pre-treatment and routine quality assurance (QA) for the abovementioned treatment. Two-dimensional displacements between the radiation isocentre and mechanical isocentre are analysed from the test; therefore, it is difficult to identify the three-dimensional (3D) isocentre position intuitively. In this study, we developed an innovative 3D WL test for SRS-QA using a novel radiochromic gel dosimeter based on a polyvinyl alcohol-iodide (PVA-I) complex that can be reused after annealing. A WL gel phantom that was consisted of the PVA-I gel dosimeter poured into a tall acrylic container and an embedded small tungsten sphere was used as a position detector. A flatbed scanner was used to analyse the isocentre position. The measured 3D isocentre accuracy from the gel-based WL test was within 0.1 mm compared with that obtained from the EPID-based WL test. Furthermore, excellent reusability of the WL gel phantom was observed in long-term SRS isocentre verification, in which clinical SRS cases involving repeated irradiation and annealing were analysed. These results demonstrate the high accuracy and reliable evaluation of the isocentre position using an innovative test. In addition, the clinical-based routine SRS-QA using the PVA-I gel dosimeter demonstrates a highly convenience while affording an easy and fast analysis process.
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http://dx.doi.org/10.1088/1361-6560/ac279d | DOI Listing |
Appl Radiat Isot
December 2024
Radiation Application Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
A gamma cell unit is used for gamma irradiation of small volume samples. Due to the sample volume, there is a dose distribution, which is imperative to be known for appropriate irradiation. In this study, samples of agarose Fricke gel dosimeters were prepared for the dose mapping of the gamma cell unit available in our laboratory.
View Article and Find Full Text PDFPhys Imaging Radiat Oncol
October 2024
Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.
Background And Purpose: During an end-to-end (E2E) test on the online workflow of the MR-linac, the performance of the treatment starting from the acquisition of pre-treatment MRI scans and ending with dose delivery is quantified. In such a test, the geometrical accuracy of the entire workflow is assessed. Ideally, the 3D geometrical accuracy of dose delivery on an MR-linac should be assessed using dosimeters that provide 3D dose distributions.
View Article and Find Full Text PDFMed Phys
October 2024
Department of Radiation Oncology, National Cancer Center Hospital East, Chiba, Japan.
Background: Comprehensive quality assurance (QA) for a seamless workflow of high-dose-rate brachytherapy, from imaging to planning and irradiation, is uncommon, and QA of the source dwell position is performed in one- or two-dimensions. Gel dosimetry using magnetic resonance imaging (MRI) is effective in verifying the three-dimensional distribution of doses for image-guided brachytherapy (IGBT). However, MRI scanners are not readily accessible, and MRI scanning is time-consuming.
View Article and Find Full Text PDFFree Radic Biol Med
November 2024
Department of Radiology, Gifu University, Gifu, Japan; Innovation Research Center for Quantum Medicine, Gifu University, Gifu, Japan; Department of Radiology, Frontier Science for Imaging, School of Medicine, Gifu University, Gifu, Japan.
The dose of X-ray irradiation is commonly measured by point assessment with an ionization chamber dosimeter. However, to achieve spatially accurate delivery of X-ray to avoid the exposure to normal tissues, an accurate imaging method for spatially and quantitatively detecting exposure is required. Herein, we present a novel method to visualize X-ray exposure using low-field dynamic nuclear polarization magnetic resonance imaging (DNP-MRI) with nitroxyl radical tempol as the chemical dosimeter.
View Article and Find Full Text PDFMed Phys
January 2025
Toshiba Energy Systems & Solutions Corporation, Kawasaki, Japan.
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