Background: Given possible impairment in psychomotor functioning related to acute cannabis intoxication, we explored whether smartphone-based sensors (e.g., accelerometer) can detect self-reported episodes of acute cannabis intoxication (subjective "high" state) in the natural environment.
Methods: Young adults (ages 18-25) in Pittsburgh, PA, who reported cannabis use at least twice per week, completed up to 30 days of daily data collection: phone surveys (3 times/day), self-initiated reports of cannabis use (start/stop time, subjective cannabis intoxication rating: 0-10, 10 = very high), and continuous phone sensor data. We tested multiple models with Light Gradient Boosting Machine (LGBM) in distinguishing "not intoxicated" (rating = 0) vs subjective cannabis "low-intoxication" (rating = 1-3) vs "moderate-intensive intoxication" (rating = 4-10). We tested the importance of time features (i.e., day of the week, time of day) relative to smartphone sensor data only on model performance, since time features alone might predict "routines" in cannabis intoxication.
Results: Young adults (N = 57; 58 % female) reported 451 cannabis use episodes, mean subjective intoxication rating = 3.77 (SD = 2.64). LGBM, the best performing classifier, had 60 % accuracy using time features to detect subjective "high" (Area Under the Curve [AUC] = 0.82). Combining smartphone sensor data with time features improved model performance: 90 % accuracy (AUC = 0.98). Important smartphone features to detect subjective cannabis intoxication included travel (GPS) and movement (accelerometer).
Conclusions: This proof-of-concept study indicates the feasibility of using phone sensors to detect subjective cannabis intoxication in the natural environment, with potential implications for triggering just-in-time interventions.
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http://dx.doi.org/10.1016/j.drugalcdep.2021.108972 | DOI Listing |
Mol Psychiatry
January 2025
Icahn School of Medicine at Mount Sinai, Departments of Neuroscience, Psychiatry; Addiction Institute of Mount Sinai, New York, NY, USA.
Anxiety disorders are one of the top contributors to psychiatric burden worldwide. Recent years have seen a dramatic rise in the potential anxiolytic properties ascribed to cannabidiol (CBD), a non-intoxicating constituent of the Cannabis Sativa plant. This has led to several clinical trials underway to examine the therapeutic potential of CBD for anxiety disorders.
View Article and Find Full Text PDFJ Stud Alcohol Drugs
January 2025
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine.
Background: A handful of studies have examined differences in the subjective effects and consequences of utilizing different modes of cannabis (e.g., smoking vs.
View Article and Find Full Text PDFVet Med Int
January 2025
Group of Veterinary Investigation GIVET, Program of Veterinary Medicine, Lasallian University Corporation, Bogotá, Colombia.
Marijuana poisoning in canines is still considered a taboo topic. Poisoning in pets is becoming increasingly common, in many cases resulting in severe clinical signs, such as ataxia, urinary incontinence, mydriasis, depression, and hyperesthesia. Colombia does not have any reliable test for the diagnosis of exposure to cannabis in animals, and it is not an obligation to report this kind of poisoning to the authorities.
View Article and Find Full Text PDFJ Psychoactive Drugs
January 2025
Department of Psychology, The University of British Columbia, Kelowna, BC, Canada.
The increasing acceptance of cannabis use, and policy changes in several jurisdictions has led researchers and public health experts to call for a standard cannabis dose. Standard dosing units are useful tools for regulation, substance use guidelines, data collection, consistency of research, as a means of communicating low-risk recommendations and dose-related effects, and for self-monitoring. Efforts to standardize cannabis dose have focused on cannabinoid content without considering tolerance or mode.
View Article and Find Full Text PDFCannabis
December 2024
Peter Boris Centre for Addictions Research, St. Joseph's Healthcare Hamilton and McMaster University.
Unlabelled: Although Canada legalized cannabis beverages in 2019, most available research on acute cannabis intoxication derives from dried flower and edible products. The distinct bioavailability and pharmacokinetic properties of phytocannabinoids ingested from beverages, however, contribute to significantly different acute and long-term effects that need to be better understood to ensure consumer safety.
Objective: This review investigates existing cannabis beverage literature, with a particular focus on acute intoxication effects.
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