White dot syndromes (WDS) represent a heterogeneous group of inflammatory diseases, primarily affecting the outer retina, choriocapillaris and choroid. Recent advances in the field of ocular imaging and development of new technologies, including optical coherence tomography angiography (OCT-A), have allowed a better characterization of the morphology of these conditions. This review will analyse the WDS from an imaging-based perspective, providing a better understanding of the pathophysiology underlying these disorders.
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http://dx.doi.org/10.1186/s12348-021-00261-3 | DOI Listing |
Alzheimers Dement
December 2024
University of California, San Diego, La Jolla, CA, USA.
Background: Pathological changes of Alzheimer's disease (AD) occur in the locus coeruleus (LC) years before clinical symptoms. This may affect LC activity that can be indexed by changes in pupil dilation. AD also disrupts connections between related but functionally distinct cortical areas leading to visual feature binding deficits.
View Article and Find Full Text PDFCureus
November 2024
Department of Ophthalmology, Unidade Local de Saúde (ULS) Santa Maria, Lisbon, PRT.
Benign yellow dot maculopathy (BYDM) is a recently described rare, asymptomatic, early onset, and non-progressive macular phenotype. It is characterized by the presence of multiple white-yellow dots encircling the fovea, which are hyperautofluorescent on fundus autofluorescence. Here, we expand on the few reports available by presenting a case series of five Portuguese patients with clinical BYDM phenotype and congruent multimodal imaging, including the second reported unilateral case.
View Article and Find Full Text PDFAustralas J Dermatol
December 2024
Department of Medical Area, Institute of Dermatology, University of Udine, Udine, Italy.
Introduction: Ultraviolet-based dermoscopy may support the recognition of scabies, yet neither accuracy analyses nor data on skin of colour are available. The aim of this multicentric observational retrospective was to investigate the diagnostic accuracy of polarised and ultraviolet-induced fluorescence (UVF) dermoscopic examination in both fair and dark skin, also assessing possible differences according to the skin tone.
Methods: Consecutive patients with a diagnosis of scabies were eligible.
ACS Appl Mater Interfaces
December 2024
School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China.
Developing hybrid fluorescence (FL)/room-temperature phosphorescent (RTP) materials in dry-state, aqueous, and organic solvents holds paramount importance in broadening their applications. However, it is extremely challenging due to dissolved oxygen and solvent-assisted relaxation causing RTP quenching in an aqueous environment and great dependence on SiO-based materials. Herein, an efficient endogenetic carbon dot (CD) strategy within melamine-formaldehyde (MF) microspheres to activate RTP of CDs has been proposed through the pyrolysis of isophthalic acid (IPA) molecules and branched-chain intra-microspheres.
View Article and Find Full Text PDFJ Phys Chem Lett
December 2024
Key Laboratory of Colloid and Interface Chemistry of Ministry of Education and School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China.
Carbon dots (CDs) with circularly polarized afterglow (CPA) materials have drawn increasing attention as cutting-edge research in the field of chiral luminescence owing to their promising applications in various fields. However, due to the weak optical activity of chiral CDs and the limited afterglow color of phosphorescent CDs, it is still a formidable challenge to construct multicolor CD-based CPA materials with a high luminescence dissymmetry factor (). Herein, positively charged aggregation-induced emission (AIE) CDs were prepared using dithiosalicylic acid and ionic liquid as precursors.
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