Acute respiratory failure on a low dose of amiodarone - is it an underdiagnosed and undertreated condition?

Respir Med Case Rep

Department of Rheumatology and Clinical Immunology, University Hospital Centre Split, Spinčićeva 1, 21000, Split, Croatia.

Published: September 2021

Amiodarone-induced pulmonary toxicity (AIPT) has a variety of presentations. Amiodarone use has been rarely associated with the development of acute respiratory failure. We present a patient with a history of paroxysmal atrial fibrillation who developed acute respiratory distress syndrome despite taking a low dose of amiodarone and having no risk or precipitating factors. The diagnosis of AIPT was made after drug discontinuation and exclusion of other potential causes. The development of acute respiratory failure due to AIPT is often underdiagnosed and undertreated. Better identification of risk factors and developing appropriate diagnostic tools for risk stratification of patients receiving amiodarone is mandatory.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429964PMC
http://dx.doi.org/10.1016/j.rmcr.2021.101500DOI Listing

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