AI Article Synopsis
- - The study examined clinical outcomes and virus detection rates in newborns from mothers who tested positive for SARS-CoV-2, involving 130 neonates from 122 mothers.
- - Among these neonates, 12% tested positive for the virus; they were mainly delivered via cesarean section and showed higher rates of admission and complications like bradycardia compared to those who tested negative.
- - Overall, while there was documented perinatal transmission and some complications, the short-term health outcomes for most neonates were relatively good.
Article Abstract
Background: The aim of the study was to investigate the clinical outcomes and rate of virus detection in neonates born to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive mothers.
Methods: This prospective study included neonates born to SARS-CoV-2-positive mothers, documenting their viral polymerase chain reaction results and clinical outcomes.
Results: Of the 130 neonates born to 122 SARS-CoV-2-positive mothers, 12% tested positive. Most (62%) neonates were delivered via cesarean section at an average gestational age of 36 weeks, with a birth weight of 2,900 g. Only 38% neonates required admission. SARS-CoV-2-positive infants were born at a significantly lower gestational age; had a significantly lower birth weight; and had significantly higher admission rates, surfactant therapy, and bradycardia than SARS-CoV-2-negative infants. There was no significant difference in mortality rates.
Conclusion: This study documents perinatal transmission of SARS-CoV-2. It reports for the first time the occurrence of neonatal bradycardia as a complication of maternal SARS-CoV-2 infection. Despite that, neonates born to SARS-CoV-2-positive mothers had relatively good short-term outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425792 | PMC |
| http://dx.doi.org/10.14740/jocmr4578 | DOI Listing |
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